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简纪常,二级教授,博士,博士生导师,现任研究生院院长。教育部高等学校水产类专业教学指导委员会委员,广东省水产经济动物病原生物学及流行病学重点实验室和水产经济动物病害广东省高等学校重点实验室副主任。曾被评为湛江市“十大”优秀青年、广东省教工委优秀共产党员和湛江市五一劳动奖章。入选广东省普通高等学校“千百十工程”省级培养对象、广东省扬帆计划高层次人才。中国水产学会理事、中国水产学会鱼病专业委员会委员,中国微生物学会海洋微生物学分会理事、国际鱼类免疫学会员、广东省海洋与湖沼学会和中国海洋学会热带海洋分会常务理事、湛江市水产动物疾病防治学会召集人。领导的...   详细>>

被引量:3,276H指数:26SCI-EXPANDED: 179EI: 3北大核心: 123CSCD: 106

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476 条 记 录,以下是 1-30

Effects of traditional Chinese medicine on nonspecific immunity and disease resistance of large yellow croaker, Pseudosciaena crocea (Richardson)
AQUACULTUREJian J. Wu Z.  出版年:2003
The influence of traditional Chinese medicine (TCM) formulated from Astragalus Root (Radix astragalin seu Hedysari) and Chinese Angelica Root (Radix angelicae sinensis) at the rate of 5:1 (w/w) on nonspecific immunity in...
中草药对建鲤非特异性免疫功能的影响
《大连水产学院学报》简纪常 吴灶和  出版年:2002
用添加中草药的鲤配合饲料饲喂建鲤(Cyprinnus var.Jian)后,测定了建鲤非特异性免疫指标。饲喂药饵Ⅰ 10、15、30 d后,氯化硝基四氮唑兰(NBT)阳性细胞数分别为 27±3.45、39±6.04和 3...
关键词:非特异性免疫功能  建鲤  中草药  NBT阳性细胞  溶菌酶  免疫增强剂  饲料添加剂  被引量:133
Effects of a commercial probiotic BS containing Bacillus subtilis and Bacillus licheniformis on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus
FISH & SHELLFISH IMMUNOLOGYAbarike, Emmanuel Delwin Cai, Jia Lu, Yishan Yu, Huang Chen, Lihua Jian, Jichang Tang, Jufen Jun, Liang Kuebutornye, Felix K. A.  出版年:2018
The present study evaluated a commercial probiotic designated as BS (a mix of B. subtilis and B. licheniformis) to ascertain its efficacy and the dose necessary to improve growth, immune response, and disease resistance ...
Cloning and expression of heat shock protein 70 gene in the haemocytes of pearl oyster (Pinctada fucata, Gould 1850) responding to bacterial challenge
FISH & SHELLFISH IMMUNOLOGYWang, Zhongliang Wu, Zaohe Jian, Jichang Lu, Yishan  出版年:2009
The cdNA of pearl oyster Pinctada fucata Hsp70 (designated PFHsp70) was cloned by EST and rapid amplification of cdNA ends (RACE) techniques. The full length of PFHsp70 cdNA was 2376 bp, consisting of a 5'-terminal untra...
Complete Genome Sequence of Streptococcus agalactiae ZQ0910, a Pathogen Causing Meningoencephalitis in the GIFT Strain of Nile Tilapia (Oreochromis niloticus)
JOURNAL OF BACTERIOLOGYWang, Bei Jian, Jichang Lu, Yishan Cai, Shuanghu Huang, Yuchong Tang, Jufen Wu, Zaohe  出版年:2012
Streptococcus agalactiae (group B streptococcus [GBS]) is a pathogen that causes meningoencephalitis in Nile tilapia (Oreochromis niloticus). Here, we reported the complete genome sequence of S. agalactiae strain ZQ0910,...
Comprehensive identification and profiling of Nile tilapia (Oreochromis niloticus) microRNAs response to Streptococcus agalactiae infection through high-throughput sequencing
FISH & SHELLFISH IMMUNOLOGYWang, Bei Gan, Zhen Cai, Shuanghu Wang, Zhongliang Yu, Dapeng Lin, Ziwei Lu, Yishan Wu, Zaohe Jian, Jichang  出版年:2016
MicroRNAs are a kind of small non-coding RNAs that participate in various biological processes. Deregulated microRNA expression is associated with several types of diseases. Tilapia (Oreochromis niloticus) is an importan...
Immunostimulatory effects of artificial feed supplemented with a Chinese herbal mixture on Oreochromis niloticus against Aeromonas hydrophila
FISH & SHELLFISH IMMUNOLOGYTang, Jufen Cai, Jia Liu, Ran Wang, Jiamin Lu, Yishan Wu, Zaohe Jian, Jichang  出版年:2014
The effects of a Chinese herbal mixture (CHM) composed of astragalus, angelica, hawthorn, Licorice root and honeysuckle on immune responses and disease resistant of Nile tilapia (Oreochromis niloticus GIFT strain) were i...
恩诺沙星在眼斑拟石首鱼体内的药物代谢动力学
《中国兽医学报》简纪常 吴灶和 陈刚  出版年:2005
应用反相高效液相色谱法 (RP- HPL C)研究了恩诺沙星在眼斑拟石首鱼 (Sciaenops ocellatus)体内的药物代谢动力学。实验数据经 DAS药代动力学分析软件分析后得出 :腹腔注射组血浆的药时数据符合一...
关键词:眼斑拟石首鱼  恩诺沙星  药物代谢动力学  反相高效液相色谱法  被引量:45
Molecular characterization and expression of cd2BP2 in Nile tilapia (Oreochromis niloticus) in response to Streptococcus agalactiae stimulus
GENEGan, Zhen Wang, Bei Lu, Yishan Cai, Shuanghu Cai, Jia Jian, JiChang Wu, Zaohe  出版年:2014
cd2BP2 (cd2 cytoplasmic tail binding protein 2), one of several proteins interacting with the cytoplasmic tail of cd2, plays a crucial role in cd2-triggered T cell activation and nuclear splicing. The studies on cd2BP2 h...
Influence of traditional Chinese medicine and Bacillus species (TCMBS) on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus
AQUACULTURE RESEARCHAbarike, Emmanuel Delwin Jian, Jichang Tang, Jufen Cai, Jia Yu, Huang Chen Lihua Jun, Liang  出版年:2018
Multispecies herbs and probiotic bacteria offered to fish might enhance their immune response and increase disease resistance, but the dose effects of herbal-probiotic application remain unclear. Therefore, the effect of...
Single-cell RNA-seq reveals different subsets of non-specific cytotoxic cells in teleost
GENOMICSNiu, Jinzhong Huang, Yu Liu, Xinchao Zhang, Zhiqiang Tang, Jufen Wang, Bei Lu, Yishan Cai, Jia Jian, Jichang  出版年:2020
Non-specific cytotoxic cells (NCC) are important cytotoxic leukocytes in teleost immune system. However, the NCC subsets have not been clarified. Thus, we create a comprehensive cell map of similar to 24,062 head kidney-...
利用有益微生物改善养殖生态环境的研究
《湛江海洋大学学报》陈家长 简纪常 胡庚东 吴伟 瞿建宏  出版年:2002
研究了噬菌蛭弧菌在实验室条件下对水产养殖中常见病菌的裂解能力及噬菌蛭弧菌和光合细菌对池塘生态环境的改善作用。结果表明 ,噬菌蛭菌对嗜水气单胞菌具有裂解作用 ,噬菌蛭弧菌和光合细菌结合使用对养殖环境具有明显的改善作用。 2...
关键词:有益微生物  养殖生态环境  噬菌蛭弧菌  光合细菌  嗜水气单胞菌  被引量:38
Transcriptome analysis of the pearl oyster (Pinctada fucata) hemocytes in response to Vibrio alginolyticus infection
GENEWang, Zhongliang Wang, Bei Chen, Gang Jian, Jichang Lu, Yishan Xu, Youhou Wu, Zaohe  出版年:2016
The pearl oyster Pinctada fucata is cultured widely for production of marine pearls in China, while mass mortalities, likely related to pathogenic infections, have occurred frequently in juvenile, mother and operated oys...
Construction of a Vibrio alginolyticus hopPmaJ (hop) mutant and evaluation of its potential as a live attenuated vaccine in orange-spotted grouper (Epinephelus coioides)
FISH & SHELLFISH IMMUNOLOGYPang, Huanying Qiu, Mingsheng Zhao, Jingmin Hoare, Rowena Monaghan, Sean J. Song, Dawei Chang, Yunsheng Jian, Jichang  出版年:2018
Vibrio alginolyticus, a bacterial pathogen in fish and humans, expresses a type III secretion system (T3SS) that is critical for pathogen virulence and disease development. However, little is known about the associated e...
海水网箱养殖军曹鱼弧菌病病原的分离及其特性
《中国兽医学报》简纪常 吴灶和 陈刚 曾敏玲  出版年:2003
从海水网箱养殖的患病军曹鱼 (Rachycentron canadum)的肾脏、肝脏等实质器官及腹水中分离出 1株致病菌即JA- 4 6菌。其特点如下 :革兰氏阴性短杆菌 ,极端单鞭毛 ,大小为 (1~ 2 )μm× (...
关键词:军曹鱼  海水网箱养殖  弧菌病  创伤弧菌  药敏试验  生物学特性  被引量:33
Loop-mediated isothermal amplification method for rapid detection of Vibrio alginolyticus, the causative agent of vibriosis in mariculture fish
LETTERS IN APPLIED MICROBIOLOGYCai, S. H. Lu, Y. S. Wu, Z. -H. Jian, J. C. Wang, B. Huang, Y. C.  出版年:2010
Aims: The purpose of this study was to develop a loop-mediated isothermal amplification (LAMP) method for the rapid, sensitive and simple detection of Vibrio alginolyticus in mariculture fish. Methods and Results: LAMP p...
NK-lysin from Oreochromis niloticus improves antimicrobial defence against bacterial pathogens
FISH & SHELLFISH IMMUNOLOGYHuang, Yu Zheng, Qi Niu, Jinzhong Tang, Jufen Wang, Bei Abarike, Emmanuel Delwin Lu, Yishan Cai, Jia Jian, Jichang  出版年:2018
NK-lysin, an effector of cytotoxic T cells and natural killer cells, is a potent antimicrobial peptide widely distributed in mammals. Homologues of NK-lysin have been discovered in several teleost species, but only sever...
A tandem-repeat galectin involved in innate immune response of the pearl oyster Pinctada fucata
MARINE GENOMICSWang, Zhongliang Jian, Jichang Lu, Yishan Wang, Bei Wu, Zaohe  出版年:2011
The cdNA of a tandem-repeat galectin from the pearl oyster Pinctada fucata (designated PfGal) was cloned by expressed sequence tag (EST) and rapid amplification of cdNA ends (RACE) techniques. The full-length cdNA of PfG...
Conservation of structural and interactional features of cd28 and cd80/86 molecules from Nile tilapia (Oreochromis niloticus)
FISH & SHELLFISH IMMUNOLOGYHuang, Yu Wang, Zhiwen Zheng, Qi Tang, Jufen Cai, Jia Lu, Yishan Jian, Jichang  出版年:2018
Interaction of cd28 with cd80 or cd86 molecules provides a costimulatory signals required in T cell activation. In this study, we cloned and analyzed a cd28 gene (On-cd28) and a cd80/86 gene (On-cd80/86) from Nile tilapi...
溶藻弧菌脂多糖对石斑鱼免疫功能的影响
《水生生物学报》简纪常 叶剑敏 吴灶和  出版年:2004
关键词:石斑鱼  溶藻弧菌  脂多糖  免疫功能  被引量:29
卵形鲳鲹结节病病原的分离与鉴定
《广东海洋大学学报》黄郁葱 简纪常 吴灶和 鲁义善 余坦健  出版年:2008
从湛江港、阳江闸坡海水网箱养殖的患结节病卵形鲳鲹(Trachinotus ovatus)中分离一株细菌,回归感染结果证明该菌是引起卵形鲳鲹结节病的病原,对卵形鲳鲹半致死浓度为45 g-1。该菌株呈革兰阳性,好氧,具有弱抗...
关键词:卵形鲳鲹  结节病  诺卡氏菌  16S  rDNA  被引量:29
VscO, a putative T3SS chaperone escort of Vibrio alginolyticus, contributes to virulence in fish and is a target for vaccine development
FISH & SHELLFISH IMMUNOLOGYZhou, Zejun Pang, Huanying Ding, Yu Cai, Jia Huang, Yucong Jian, Jichang Wu, Zaohe  出版年:2013
Type III secretion system (T3SS) in Vibrio alginolyticus is essential for its pathogenesis. VscO's homologous proteins FliJ, InvI and YscO have been suggested to be putative chaperone escorts although its function in V. ...
Protection against Vibrio alginolyticus in pearl gentian grouper (female Epinephelus fuscoguttatus x male Epinephelus lanceolatu) immunized with an acfA-deletion live attenuated vaccine
FISH & SHELLFISH IMMUNOLOGYChen, Yanyan Cai, Shuanghu Jian, Jichang  出版年:2019
Vibrio alginolyticus is well-known as an opportunistic Grain-negative pathogen, which endangers the development of global aquaculture as well as human health. In this study, a Delta acfA mutant strain and complementation...
溶藻弧菌疫苗对凡纳滨对虾免疫功能的影响
《湛江海洋大学学报》曹剑香 简纪常 吴灶和  出版年:2004
应用溶藻弧菌疫苗饲喂凡纳滨对虾,测定了弧菌疫苗对凡纳滨对虾免疫指标的影响以及 疫苗的免疫保护作用。结果发现,投喂弧菌疫苗后,溶菌活力在12~20d内迅速增强,在20d时 活力达到最高,VF1组高于VF2和VF3组...
关键词:凡纳滨对虾  免疫指标  免疫保护率  影响因素  溶藻弧菌疫苗  被引量:27
水体中NH_3-N对建鲤非特异性免疫功能的影响
《湛江海洋大学学报》陈家长 简纪常 胡庚东 尤洋  出版年:2000
用 0 .1、0 .5、1.0、2 .0和 5.0 mg/ L NH3- N分别刺激建鲤 10 d和 2 0 d后 ,测定了建鲤非特异性免疫指标 ,估测不同浓度的 NH3- N对建鲤非特异性免疫指标的影响。 0 .1、0...
关键词:建鲤  NH3-N  非特异性免疫功能  水体污染  被引量:26
Traditional Chinese Medicine Enhances Growth, Immune Response, and Resistance to Streptococcus agalactiae in Nile Tilapia
JOURNAL OF AQUATIC ANIMAL HEALTHAbarike, Emmanuel Delwin Jian, Jichang Tang, Jufen Cai, Jia Yu, Huang Chen, Lihua  出版年:2019
Herbal supplements are suitable for improving fish health and combating diseases in fish culture. However, the mechanism of action of many herbal mixtures remains unclear. This study was conducted to evaluate the effects...
复方中草药对吉富罗非鱼生长及肠道菌群的影响
《广东海洋大学学报》汤菊芬 吴灶和 简纪常 鲁义善 王蓓  出版年:2009
将A、B、C三种复方中草药分别按质量分数1.5%的比例添加到罗非鱼商品饲料中,喂养初始体重约16.58±0.48g的吉富罗非罗28d,通过测定罗非鱼的增重率、饲料系数、肠道菌群等指标,研究三种复方中草药制剂对罗非鱼生长性...
关键词:中草药  吉富罗非鱼  生长  肠道菌群  被引量:26
Identification and characterization of tumor necrosis factor receptor (TNFR)-associated factor 3 from humphead snapper, Lutjanus sanguineus
FISH & SHELLFISH IMMUNOLOGYCai, Jia Xia, Hongli Huang, Yucong Tang, Jufen Jian, Jichang Wu, Zaohe Lu, Yishan  出版年:2015
Tumor necrosis factor receptor (TNFR)-associated factor 3(TRAF3) is a key regulator in TNFR and Toll-like receptor (TLRs)/RIG-I-like receptors (RLRs) signal pathway. Here, a TRAF3 gene (Ls-TRAF3, GenBank Accession No: Kj...
A comprehensive profile of the tilapia (Oreochromis niloticus) circular RNA and circRNA-miRNA network in the pathogenesis of meningoencephalitis of teleosts
MOLECULAR OMICSFan, Bolin Chen, Funuan Li, Yuan Wang, Zhongliang Wang, Zhiwen Lu, Yishan Wu, Zaohe Jian, Jichang Wang, Bei  出版年:2019
The pathogenesis of tilapia meningoencephalitis is still unclear, where the involvement of circRNA is considered for its active role as a `` miRNA sponge''. Therefore, we aimed to investigate the profile of circRNA in ti...
Draft Genome Sequence of Nocardia seriolae ZJ0503, a Fish Pathogen Isolated from Trachinotus ovatus in China
MICROBIOLOGY RESOURCE ANNOUNCEMENTSXia, Liqun Cai, Jia Wang, Bei Huang, Yucong Jian, Jichang Lu, Yishan  出版年:2015
Nocardia seriolae is a pathogen that causes nocardiosis in marine and freshwater fish. Here, we report the draft genome sequence of N. seriolae strain ZJ0503, which was isolated from Trachinotus ovatus in Guangdong, Chin...
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