文献类型：期刊文献

中文题名：有抗病毒活性的苯并咪唑苯氧乙酸乳糖酯的催化合成

英文题名：Catalytic synthesis of antiviral active benzimidazolyl phenoxyacetic acid lactopyranosyl saccharide carboxylate

作者：陈洪[1];谢建英[1];黄思庆[1]

机构：[1]广东海洋大学应化系,广东湛江524088

年份：2005

卷号：17

期号：6

起止页码：799

中文期刊名：化学研究与应用

外文期刊名：Chemical Research and Application

收录：CSTPCD、、北大核心2004、CSCD2011_2012、北大核心、CSCD

基金：广东省教育厅自然科学基金资助课题

语种：中文

中文关键词：苯并咪唑苯氧乙酸乳糖酯;抗病毒活性;DMAP/Et3N

外文关键词：benzimidazolyl phenoyacetic acid O - acetyllactopyranosyl saccharide carboxylate ;TMV; DMAP/Et3N

中文摘要：4-dimethylpyridine（DMAP） was used as catalyst for preparing benzimidazolyl phenoxyacetic acid O-acetyllactopyranosyl saccharide carboxylate and triethylamine（Et3N） was used as deacid reagent.Three saccharide carboxylates were synthesized from saccharide carboxylation at room temperature in the system of DMAP/Et3N with nitro-containing,trifluoromethyl benzimidazolyl phenoxyacetic acid with as lead compounds.The catalytic mechanism of DMAP/Et3N was discussed.The results showed that DMAP is a effective catalyst.The yields can reach over 52.7%.The test indicated that the compounds showed better antiviral activity against tobacco mosaie virus（TMV）.

外文摘要：4- dimethylpyridine （DMAP） was used as catalyst for preparing benzimidazoloyl phenoxyacefic acid O -acetyllactopyrmmsyl saceha- ride carboxylate and triethylamine（Et3N） was used as deacid reagent. Three saccharide carboxylates were synthesized from saecharide carboxylation at room temperature in the system of DMAP/Et3N with nitro - containing,trifluoromethyl benzimidazolyl phenoxyacetic acid with as lead compounds. The catalytic mechanism of DMAP/Et3N was discussed. The results showed that DMAP is a effective catalyst. The yields can reach over 52. 7%. The test indicated that the compounds showed better antiviral activity against tobacco mosaie virus（TMV）.