文献类型：期刊文献

英文题名：Therapeutic effect of daucosterol on DSS-induced colitis in mice

作者：Liang J.; Yang H.; Chen K.; Cai J.; Wang Y.; Yong Y.

机构：[1]College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China

年份：2026

卷号：26

期号：1.0

外文期刊名：BMC Microbiology

收录：Scopus(收录号：2-s2.0-105027182329)

语种：英文

外文关键词：Daucosterol; DSS; Gut microbiota; Ulcerative colitis

外文摘要：Ulcerative colitis (UC) is an intestinal disease caused by multiple factors that severely affects the health of humans and animals. In this study, a DSS-induced mouse colitis model was utilized to investigate the ability of daucosterol (DAU) to alleviate colitis and its underlying mechanism of action. The experimental results showed that DAU could alleviate the clinical symptoms of colitis in mice, reduce the expression of proinflammatory cytokines (IL-1β, IL-6, and TNF-α) in mouse serum, and modulate the gut microbiota to alleviate DSS-induced colitis in mice. In conclusion, DAU has great potential in the prevention of colitis. ? The Author(s) 2025.