文献类型：期刊文献

英文题名：Mucormycosis (black fungus) ensuing COVID-19 and comorbidity meets- Magnifying global pandemic grieve and catastrophe begins

作者：Pushparaj, Karthika[1];Bhotla, Haripriya Kuchi[2];Arumugam, Vijaya Anand[3];Pappusamy, Manikantan[2];Easwaran, Murugesh[4];Liu, Wen-Chao[5];Issara, Utthapon[6];Rengasamy, Kannan R. R.[7];Meyyazhagan, Arun[2];Balasubramanian, Balamuralikrishnan[8]

机构：[1]Avinashilingam Inst Home Sci & Higher Educ Women, Sch Biosci, Dept Zool, Coimbatore 641043, Tamil Nadu, India;[2]CHRIST Deemed Univ, Dept Life Sci, Bengaluru 560076, Karnataka, India;[3]Bharathiar Univ, Dept Human Genet & Mol Biol, Coimbatore 641046, Tamil Nadu, India;[4]Int Ctr Genet Engn & Biotechnol, New Delhi 110067, India;[5]Guangdong Ocean Univ, Coll Coastal Agr Sci, Dept Anim Sci, Zhanjiang 524088, Peoples R China;[6]Rajamangala Univ Technol Thanyaburi, Fac Sci & Technol, Div Food Sci & Technol Management, Pathum Thani 12110, Thailand;[7]Univ Limpopo, Green Biotechnol Res Ctr Excellence, Private Bag X1106, ZA-0727 Polokwane, Sovenga, South Africa;[8]Sejong Univ, Coll Life Sci, Dept Food Sci & Biotechnol, Seoul 05006, South Korea

年份：2022

卷号：805

外文期刊名：SCIENCE OF THE TOTAL ENVIRONMENT

收录：SCI-EXPANDED(收录号：WOS:000704389500018)、、EI(收录号：20213810916788)、Scopus(收录号：2-s2.0-85115068351)、WOS

语种：英文

外文关键词：Hyperglycemia; Ketosis; Dexamethasone; Secondary infections; Diagnosis; COVID-19 induced Mucormycosis; Comorbidity

外文摘要：Post COVID-19, mucormycosis occurred after the SARS-CoV-2 has rampaged the human population and is a scorching problem among the pandemic globally, particularly among Asian countries. Invasive mucormycosis has been extensively reported from mild to severe COVID-19 survivors. The robust predisposing factor seems to be uncontrolled diabetes mellitus, comorbidity and immunosuppression acquired through steroid therapy. The prime susceptive reason for the increase of mucormycosis cases is elevated iron levels in the serum of the COVID survivors. A panoramic understanding of the infection has been elucidated based on clinical manifestation, genetic and non- genetic mechanisms of steroid drug administration, biochemical pathways and immune modulated receptor associations. This review lime-lights and addresses the "What", "Why", "How" and "When" about the COVID-19 associated mucormycosis (CAM) ina comprehensive manner with a pure intention to bring about awareness to the common public as the cases are inevitably and exponentially increasing in India and globalcountries as well. The article also unearthed the pathogenesis of mucormycosis and its association with the COVID-19 sequela, the plausible routes of entry, diagnosis and counter remedies to keep the infection at bay. Cohorts of case reports were analysed to spotlight the link between the pandemic COVID-19 and the nightmare-mucormycosis. (c) 2021 Elsevier B.V. All rights reserved.