文献类型：期刊文献

英文题名：FUNCTIONS OF CIRCULAR RNAS INVOLVED IN ANIMAL SKELETAL MUSCLE DEVELOPMENT - A REVIEW

作者：Adu-Asiamah, Patricia[1];Leng, Qiying[1];Xu, Haidong[1];Zheng, Jiahui[1];Zhao, Zhihui[1];An, Lilong[1];Zhang, Li[1]

机构：[1]Guangdong Ocean Univ, Coll Agr, Zhanjiang 524088, Peoples R China

年份：2020

卷号：20

期号：1

起止页码：3

外文期刊名：ANNALS OF ANIMAL SCIENCE

收录：SCI-EXPANDED(收录号：WOS:000510665700001)、、Scopus(收录号：2-s2.0-85072640343)、WOS

基金：This review was supported by the National Science Foundation of China (31672412 and 31972550), the National Science Foundation of Guangdong Province (2017A030307002), the Open Project of Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and The Key Platform Projects of Innovative Strong School Engineering by Department of Education of Guangdong Province: Efficient Use of Animal Genetic Resources in the Tropics and Healthy Farming (2018302).

语种：英文

外文关键词：circRNAs; skeletal muscle; growth; myoblast; development

外文摘要：Circular RNAs (circRNAs) have been identified in the skeletal muscle of numerous species of animals. Their abundance, diversity, and their dynamic expression patterns have been revealed in various developmental stages and physiological conditions in skeletal muscles. Recently, studies have made known that circRNAs widely participate in muscle cell proliferation and differentiation. They are also involved in other life processes such as functioning as microRNA (miRNA) sponges, regulators of splicing and transcription, and modifiers of parental gene expression with emerging pieces of evidence indicating a high chance of playing a vital role in several cells and tissues, especially the muscles. Other research has emphatically stated that the growth and development of skeletal muscle are regulated by proteins as well as non-coding RNAs, which involve circRNAs. Therefore, circRNAs have been considered significant biological regulators for understanding the molecular mechanisms of myoblasts. Here, we discuss how circRNAs are abundantly expressed in muscle (myoblast) and their critical roles in growth and development.