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丛生形盔珊瑚共附生真菌的分离及其抗菌活性的筛选     被引量:3

Isolation of symbiotic fungi from the coral Galaxea fascicularis and screening of their antibacterial activities

文献类型:期刊文献

中文题名:丛生形盔珊瑚共附生真菌的分离及其抗菌活性的筛选

英文题名:Isolation of symbiotic fungi from the coral Galaxea fascicularis and screening of their antibacterial activities

作者:徐佳[1];雷晓凌[1];佘志刚[2];陈彬[2,3];肖碧红[1]

机构:[1]广东海洋大学食品科技学院,广东湛江524025;[2]中山大学化学与化学工程学院,广东广州510275;[3]西藏高原生物研究所,西藏拉萨850001

年份:2011

卷号:30

期号:5

起止页码:23

中文期刊名:中国海洋药物

外文期刊名:Chinese Journal of Marine Drugs

收录:CSTPCD、、CSCD_E2011_2012、CSCD

基金:广东海洋大学基金(E09095);国家自然科学基金(20972197);广东省科技计划项目(2010B03030004)

语种:中文

中文关键词:丛生形盔珊瑚;共附生真菌;次级代谢产物;抗菌活性;筛选

外文关键词:Galaxea fascicularis; symbiotic fungi; secondary metabolites; antibacterial activity; screening

中文摘要:目的本试验旨在研究珊瑚共附生真菌抗菌活性。方法采用96孔板培养法结合酶标仪测定。以6种常见的致病或致食品腐败的细菌为指示菌,对其共附生真菌次级代谢产物进行抗菌活性筛选,对抗菌能力及抗菌谱进行研究。结果结果表明:共分离丛生形盔珊瑚共附生真菌19株,均具有不同程度的抗菌活性。高活性菌株占52.63%,其中4-4、4-5两菌株表现出良好的抗菌活性。结论丛生形盔共附生真菌是潜在的抗菌资源,具有较高的应用潜力和综合开发前景。

外文摘要:Objective To study the antibacterial activity of cultured symbiotic fungi isolated from the coral Galaxea fascicularis.Methods The microplate reader was used to detect the antibacterial activities of the secondary metabolites from symbiotic fungi against Bacillus cereus,Bacillus subtilis,Escherichia coli,Staphylococcus epidermidis,Sarcina luteuand,Staphylococcus aureus in sterile 96-well microtitre plates.Results The results showed that all symbiotic fungal strains had antibacterial activity where 52.63% fungal had higher antibacterial activity among which 4-4,4-5 strains had broad-spectrum and strong antibacterial activity to indicator bacteria.Conclusion Symbiotic fungal strains from the coral Galaxea fascicularis are potential antibacterial resources and have wide prospect of development.

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