文献类型：期刊文献

英文题名：MECHANISM AND FUNCTIONS OF IDENTIFIED MIRNAS IN POULTRY SKELETAL MUSCLE DEVELOPMENT - A REVIEW

作者：Collins, Asiamah Amponsah[1];Zou, Kun[1];Li, Zhang[1];Ying, Su[1]

机构：[1]Guangdong Ocean Univ, Coll Agr, Zhanjiang 524025, Peoples R China

年份：2019

卷号：19

期号：4

起止页码：887

外文期刊名：ANNALS OF ANIMAL SCIENCE

收录：SCI-EXPANDED(收录号：WOS:000493751400003)、、WOS

基金：The authors are thankful to the Science and Technology Plan Project of Guangdong Province (2017A020208066) and Modern Agriculture Key Project of Zhanjiang City (2015A03003) for providing financial support.

语种：英文

外文关键词：poultry; skeletal muscle development; miRNAs; genes; proliferation; differentiation

外文摘要：Development of the skeletal muscle goes through several complex processes regulated by numerous genetic factors. Although much efforts have been made to understand the mechanisms involved in increased muscle yield, little work is done about the miRNAs and candidate genes that are involved in the skeletal muscle development in poultry. Comprehensive research of candidate genes and single nucleotide related to poultry muscle growth is yet to be experimentally unraveled. However, over a few periods, studies in miRNA have disclosed that they actively participate in muscle formation, differentiation, and determination in poultry. Specifically, miR-1, miR-133, and miR-206 influence tissue development, and they are highly expressed in the skeletal muscles. Candidate genes such as CEBPB, MUSTN1, MSTN, IGF1, FOXO3, mTOR, and NFKB1, have also been identified to express in the poultry skeletal muscles development. However, further researches, analysis, and comprehensive studies should be made on the various miRNAs and gene regulatory factors that influence the skeletal muscle development in poultry. The objective of this review is to summarize recent knowledge in miRNAs and their mode of action as well as transcription and candidate genes identified to regulate poultry skeletal muscle development.