文献类型：期刊文献

英文题名：Recent advances in enzyme immobilization based on novel porous framework materials and its applications in biosensing

作者：Feng, Yanmei[1];Xu, Ying[1];Liu, Shucheng[2];Wu, Di[3];Su, Zhuoqun[1];Chen, Guang[4];Liu, Jianghua[1];Li, Guoliang[1]

机构：[1]Shaanxi Univ Sci & Technol, Sch Food & Biol Engn, Xian, Shaanxi, Peoples R China;[2]Guangdong Ocean Univ, Coll Food Sci & Technol, Guangdong Prov Key Lab Aquat Prod Proc & Safety, Zhanjiang, Peoples R China;[3]Queens Univ Belfast, Inst Global Food Secur, Sch Biol Sci, Belfast BT9 5DL, Antrim, North Ireland;[4]Shaanxi Univ Sci & Technol, Sch Chem & Chem Engn, Xian, Shaanxi, Peoples R China

年份：2022

卷号：459

外文期刊名：COORDINATION CHEMISTRY REVIEWS

收录：SCI-EXPANDED(收录号：WOS:000790573500007)、、Scopus(收录号：2-s2.0-85124020682)、WOS

基金：This work was supported by the National Natural Science Foundation of China (32022069 and 22076115) and the Youth Innovation Team of Shaanxi Universities (21JP020).

语种：英文

外文关键词：Enzyme; Immobilization; Metal-organic frameworks; Covalent organic frameworks; Hydrogen-bonded organic frameworks; Biosensing; Contents

外文摘要：Enzyme immobilization in nano-space to maintain or even enhance their activity and stability is generally challenging. In recent years, metal-organic frameworks (MOFs), covalent organic frameworks (COFs) and hydrogen-bonded organic frameworks (HOFs), as new classes of exciting porous framework materials, have attracted much attention for many fascinating merits such as large specific surface area, specific porosity, stable framework structure, and diverse functional sites, which allow them to be considered as promising enzyme immobilization carriers. Compared with other traditional support materials, MOFs/ COFs/HOFs as the immobilization carriers of enzymes hold higher enzyme loading capacity and can significantly improve the catalytic performance and reusability of enzymes. In this paper, we firstly discuss various strategies of using MOFs/functional MOFs as matrixes to immobilize enzymes. Then, the latest research progresses of COFs and HOFs in enzyme immobilization are systematically introduced. Subsequently, the applications of enzyme-MOF/COF/HOF biocomposites in sensing, including electrochemical, colorimetric, fluorescent and other sensing strategies are comprehensively summarized. Finally, the challenges and opportunities in this field are tentatively discussed. (c) 2022 Published by Elsevier B.V.