文献类型：期刊文献

中文题名：方格星虫多糖对小鼠免疫活性的影响

英文题名：Effect of Polysaccharide Extracted from Sipunculus nudus on the Immunity of Mouse

作者：彭晓娜[1];雷晓凌[1]

机构：[1]广东海洋大学食品科技学院,广东湛江524025

年份：2007

卷号：27

期号：4

起止页码：54

中文期刊名：广东海洋大学学报

外文期刊名：Journal of Guangdong Ocean University

收录：CSTPCD

语种：中文

中文关键词：方格星虫;多糖;脾指数;胸腺指数;脾细胞;腹腔巨噬细胞

外文关键词：Sipunculus nudus L.; polysaccharide; thymus index; spleen index; splenocyte; peritoneal macrophage

中文摘要：研究了方格星虫多糖对小鼠免疫功能的影响。结果表明:方格星虫粗多糖(CSG)能够对抗环磷酰胺引起的小鼠胸腺萎缩和脾萎缩,明显拮抗白细胞减少,对正常小鼠免疫器官没有明显的增重作用;对正常小鼠腹腔巨噬细胞吞噬中性红能力有显著的增强作用。方格星虫多糖粗品(CSG)和精制多糖(SG1和SG2)能够促进小鼠脾淋巴细胞增殖,且能与ConA协同作用。

外文摘要：The effect of polysaccharide extracted from Sipunculus nudus L. on immunity of mouse was studied. The results showed that crude polysaccharide extracted from S. nudus could antagonize the decrease of spleen and thymus weight caused by cyclophosphamide, but no remarkable effect on the normal mouse, and could obviously protect against leukocytopenia; crude and purified polysaccharide could enhance the proliferation of splenocyte, and had significant phagocytic function of peritoneal macrophages especially when cooperating with ConA.