文献类型：期刊文献

英文题名：Conservation of Endangered Cordyceps sinensis Through Artificial Cultivation Strategies of C. militaris, an Alternate

作者：Krishna, Kondapalli Vamsi[1]; Balasubramanian, Balamuralikrishnan[2]; Park, Sungkwon[2]; Bhattacharya, Sukanta[1]; Kadanthottu Sebastian, Joseph[3]; Liu, Wen-Chao[4]; Pappuswamy, Manikantan[3]; Meyyazhagan, Arun[3]; Kamyab, Hesam[5,6]; Chelliapan, Shreeshivadasan[7]; Malaviya, Alok[1,8]

机构：[1] Applied and Industrial Biotechnology Laboratory, Christ University, Hosur Road, Karnataka, Bangalore, India; [2] Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, Korea, Republic of; [3] Department of Life Sciences, Christ University, Bangalore, India; [4] Department of Animal Science, College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, 524088, China; [5] Department of Biomaterials, Saveetha Dental College, and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, India; [6] Faculty of Social Sciences, Media and Communication, University of Religions and Denominations, Qom, Pardisan, Iran; [7] Department of Smart Engineering and Advanced Technology, Faculty of Artificial Intelligence, Universiti Teknologi Malaysia, Jalan Sultan Yahya Petra, Kuala Lumpur, 54100, Malaysia; [8] QuaLife Biotech Pvt. Ltd, Bangalore, India

年份：2024

外文期刊名：Molecular Biotechnology

收录：EI(收录号：20241816003469)、Scopus(收录号：2-s2.0-85191300423)

语种：英文

外文关键词：Fermentation - Metabolites

外文摘要：Cordyceps, an entomopathogenic fungus belonging to the Ascomycota phylum, is a familiar remedial mushroom that is extensively used in the traditional medicinal system, especially in South Asian nations. The significance of this genus’ members in a range of therapeutic and biotechnological applications has long been acknowledged. The exceedingly valuable fungus Ophiocordyceps sinensis (Cordyceps sinensis) is found in the alpine meadows of Bhutan, Nepal, Tibet, and India, where it is severely harvested. Driven by market demand and ecological concerns, the study highlights challenges in natural C. sinensis collection and emphasizes the shift towards sustainable artificial cultivation methods. This in-depth review navigates Cordyceps cultivation strategies, focusing on C. sinensis and the viable alternative, C. militaris. The escalating demand for Cordyceps fruiting bodies and bioactive compounds prompts a shift toward sustainable artificial cultivation. While solid-state fermentation on brown rice remains a traditional method, liquid culture, especially submerged and surface/static techniques, emerges as a key industrial approach, offering shorter cultivation periods and enhanced cordycepin production. The review accentuates the adaptability and scalability of liquid culture, providing valuable insights for large-scale Cordyceps production. The future prospects of Cordyceps cultivation require a holistic approach, combining scientific understanding, technological innovation, and sustainable practices to meet the demand for bioactive metabolites while ensuring the conservation of natural Cordyceps populations. Graphical Abstract: (Figure presented.). ? The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.