文献类型：期刊文献

英文题名：Neurobiology of rodent self-grooming and its value for translational neuroscience

作者：Kalueff, Allan V.[1,2,3,4,5];Stewart, Adam Michael[2];Song, Cai[1,6,7];Berridge, Kent C.[8];Graybiel, Ann M.[9,10];Fentress, John C.[6]

机构：[1]Guangdong Ocean Univ, Coll Food Sci & Technol, Res Inst Marine Drugs & Nutr, Key Lab Aquat Prod Proc & Safety, Zhanjiang 524088, Peoples R China;[2]ZENEREI Res Ctr, Neurosci Res Lab, Slidell, LA 70458 USA;[3]St Petersburg State Univ, Inst Translat Biomed, St Petersburg 199034, Russia;[4]Ural Fed Univ, Inst Chem Technol, Ekaterinburg 620002, Russia;[5]Ural Fed Univ, Inst Nat Sci, Ekaterinburg 620002, Russia;[6]Dalhousie Univ, Dept Psychol & Neurosci, Halifax, NS B3H 4R2, Canada;[7]China Med Univ, Grad Inst Neural Cognit Sci, Taichung 000001, Taiwan;[8]Univ Michigan, Dept Psychol, Ann Arbor, MI 48109 USA;[9]MIT, McGovern Inst Brain Res, Cambridge, MA 02139 USA;[10]MIT, Dept Brain & Cognit Sci, Cambridge, MA 02139 USA

年份：2016

卷号：17

期号：1

起止页码：45

外文期刊名：NATURE REVIEWS NEUROSCIENCE

收录：SCI-EXPANDED(收录号：WOS:000366676700008)、、Scopus(收录号：2-s2.0-84950988164)、WOS

基金：This Review is a tribute to John C. Fentress (1939-2015), a brilliant scientist, good friend and a true pioneer of ethology and neurobiology research. This study is supported by the ZENEREI Research Center (A.V.K., A.M.S.), Guangdong Ocean University (A.V.K., C.S.), St. Petersburg State University grant 1.38.201.2014 (A.V.K.), as well as by the US National Institutes of Health grants NS025529, HD028341, MH060379 (A.M.G.) and MH63649, DA015188 (K.B.). A.V.K. research is supported by the Government of Russian Federation (Act 211, contract 02.A03.21.0006 with Ural Federal University). The authors thank M. Nguyen, E.J. Kyzar and Y. Kubota for their assistance with this manuscript. They wish to acknowledge helpful suggestions from D.J. Anderson (California Institute of Technology, USA) regarding the roles of amygdala-related circuitry in grooming behaviour. The authors also thank manufacturers of neurophenotyping tools for providing information used in Supplementary information S5 (figure).

语种：英文

外文摘要：Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing pattern and is one of the most frequently performed behavioural activities in rodents. In this Review, we discuss the neurobiology of rodent self-grooming, and we highlight studies of rodent models of neuropsychiatric disorders - including models of autism spectrum disorder and obsessive compulsive disorder - that have assessed self-grooming phenotypes. We suggest that rodent self-grooming may be a useful measure of repetitive behaviour in such models, and therefore of value to translational psychiatry. Assessment of rodent self-grooming may also be useful for understanding the neural circuits that are involved in complex sequential patterns of action.