文献类型：期刊文献

英文题名：Unraveling individual and combined toxicity of microplastics and tetracycline at environment-related concentrations to coral holobionts

作者：Jiang, Shiqi[1];He, Lei[1];Cao, Linglong[1];Sun, Ruikun[1];Dai, Zhenqing[1];Liang, Yan-Qiu[1];Ren, Lei[2];Sun, Shengli[1];Li, Chengyong[1,3]

机构：[1]Guangdong Ocean Univ, Sch Chem & Environm, Zhanjiang 524088, Peoples R China;[2]Guangdong Ocean Univ, Coll Coastal Agr Sci, Zhanjiang 524088, Peoples R China;[3]Guangdong Ocean Univ, Analyt & Testing Ctr, Zhanjiang 524088, Peoples R China

年份：2025

卷号：490

外文期刊名：JOURNAL OF HAZARDOUS MATERIALS

收录：SCI-EXPANDED(收录号：WOS:001441744300001)、、EI(收录号：20251017996844)、Scopus(收录号：2-s2.0-85219500839)、WOS

基金：This work was supported by the National Natural Science Foundation of China (22474027) , Guangdong Basic and Applied Basic Research Foundation (2022B1515020091) , Scientific Research Start-upfunds of Guangdong Ocean University (060302122402) , and the Postgraduate Education Innovation Project of Guangdong Ocean University (202241) . We would like to thank Analytical and Testing Center of Guangdong Ocean University for HPLC (high performance liquid chromatograph) .

语种：英文

外文关键词：Microplastics; Tetracycline; Coral holobiont; Toxic mechanism; Symbiotic algae

外文摘要：Coral holobionts constitute the foundational organisms of coral reef ecosystems. As an emerging pollutant, the projected accumulated levels of microplastics (MPs) are expected to continue increasing. Meanwhile, due to their properties, MPs can absorb multiple other marine pollutants, such as antibiotics (ATs). However, the co-toxicity mechanism of MPs and ATs to coral holobionts remains to be explored. Here, using Zoanthus sociatus as a model organism, we investigate the individual and combined toxicity of MPs and tetracycline (TC) at environment- related concentrations to coral holobionts. Microbiomics indicate that MPs and TC increase coral holobionts bacterial species richness while concurrently reducing the microbial community structure stability. The key metabolites and enzyme activity results demonstrated that the impacts of MPs and TC on corals encompassed antioxidant capacity, detoxification capability, immune function, and lipid metabolism. Transcriptomics shows that MPs and TC disrupt coral-algae relationships mainly through host nutrition limitation and inhibition of symbiotic algae carbon/nitrogen metabolism, respectively. A synergistic effect between MPs and TC has also been observed. In contrast, coral holobionts have shown adaptability through activating coral-symbiodiniaceaebacteria interactions, mainly including: 1) enhancing the abundance of BMCs (beneficial microorganisms for