文献类型：期刊文献

英文题名：Preparation and Properties of Asymmetric Polyvinyl Pyrroli-Done/Polycaprolactone Composite Nanofiber Loaded with Tea Tree Extract

作者：Xu, Yu[1];Xie, Lei[1];Hou, Tingting[1,2,3];Wang, Di[1];Zhang, Tong[1];Li, Chengpeng[1,2,3]

机构：[1]Guangdong Ocean Univ, Sch Chem & Environm Sci, Zhanjiang 524088, Peoples R China;[2]Zhanjiang Key Lab Comprehens Utilizat Chem Res Ma, Zhanjiang 524088, Peoples R China;[3]Zhanjiang Key Lab Marine Biomat Res, Zhanjiang 524088, Peoples R China

年份：2022

卷号：14

期号：18

外文期刊名：POLYMERS

收录：SCI-EXPANDED(收录号：WOS:000859675700001)、、EI(收录号：20224012817294)、Scopus(收录号：2-s2.0-85138778255)、WOS

基金：This work was financially supported by Project of Zhanjiang Science & Technology Plan (2020A01032), Zhanjiang key laboratory of comprehensive utilization of chemical research for marine resources (No. A14457); Zhanjiang key laboratory of marine bio-materials research (No. A15445); Project of enhancing school with innovation of Guangdong Ocean University [No. GDOU2017052502]; Innovation and Entrepreneurship Training Team Program of Guangdong Ocean University (No. 521201004029).

语种：英文

外文关键词：nanofiber; polyvinyl pyrrolidone; antibacterial activity; antioxidant activity

外文摘要：To develop a novel asymmetric nanofiber membrane with antioxidant and antibacterial activities, biocompatible polyvinyl pyrrolidone (PVP) and polycaprolactone (PCL) were used as carriers to load water-soluble tea tree extract (TTE) and hydrophobic tea tree oil (TTO) via electrospinning and electrostatic spraying, respectively, which was named as TTE-PVP-3/TTO-PCL. The results show that uniform TTE-PVP nanofibers with an average diameter of 95 +/- 27 nm could be obtained when the mass ratio of TTE to PVP was set as 1:3. Homogeneous TTO/PCL microspheres with an average size of 4.38 +/- 0.79 mu m could be obtained when the propulsion speed was 0.08 mm/min and the voltage was 10 KV. The activity study showed that TTE could only improve the antioxidant activity of TTE-PVP-3/TTO-PCL, while TTO could improve the antibacterial activity effectively. Under experimental conditions, the inhibition zones of TTE-PVP-3/TTO-PCL against Staphylococcus aureus and Escherichia coli were 7.50 +/- 0.48 mm and 9.55 +/- 0.45 mm, respectively, and its scavenging rates for 2,2-diphenylpicrylhydrazyl (DHPP) and hydroxyl radical were 59.79 +/- 4.10% and 61.02 +/- 4.95%, respectively. In conclusions, TTE-PVP-3/TTO PCL can be potentially used as a new kind of anti-oxidative and antibacterial wound dressings.