文献类型：期刊文献

英文题名：NaCl Promotes the Efficient Formation of Haematococcus pluvialis Nonmotile Cells under Phosphorus Deficiency

作者：Li, Feng[1,2,3,4];Zhang, Ning[1];Zhang, Yulei[1];Lian, Qingsheng[1];Qin, Caiying[1];Qian, Zuyuan[1];Wu, Yanqi[1];Yang, Zhiyuan[1];Li, Changling[1];Huang, Xianghu[1];Cai, Minggang[1,2,3,4]

机构：[1]Guangdong Ocean Univ, Coll Fisheries, Zhanjiang 524088, Peoples R China;[2]Xiamen Univ, Fujian Prov Key Lab Coastal Ecol & Environm Studi, Xiamen 361102, Peoples R China;[3]Xiamen Univ, Key Lab Marine Chem & Appl Technol, Xiamen 361102, Peoples R China;[4]Xiamen Univ, Coll Ocean & Earth Sci, Xiamen 361102, Peoples R China

年份：2021

卷号：19

期号：6

外文期刊名：MARINE DRUGS

收录：SCI-EXPANDED(收录号：WOS:000666206400001)、、WOS

基金：This research was mainly supported by Xiamen Southern Ocean Technology Center of China under Grant (number 14CZP035HJ09) and partly funded by Xiamen Scientific and Technologic Projects under Grant (number 3052Z20031086 and 3052Z20123004); Marine Science Base Scientific Research Training and Scientific Research Ability Enhancement Project of Xiamen University under Grant (number J1210050); Xiamen University Training Program of Innovation and Entrepreneurship for Undergraduates under Grant (number 2016X0619); and the Special Funds for Scientific Research of Marine Public Welfare Industry under Grant (number 201305016).

语种：英文

外文关键词：Haematococcus pluvialis; astaxanthin; nonmotile cells; phosphorus deficiency

外文摘要：Natural astaxanthin helps reduce the negative effects caused by oxidative stress and other related factors, thereby minimizing oxidative damage. Therefore, it has considerable potential and broad application prospects in human health and animal nutrition. Haematococcus pluvialis is considered to be the most promising cell factory for the production of natural astaxanthin. Previous studies have confirmed that nonmotile cells of H. pluvialis are more tolerant to high intensity of light than motile cells. Cultivating nonmotile cells as the dominant cell type in the red stage can significantly increase the overall astaxanthin productivity. However, we know very little about how to induce nonmotile cell formation. In this work, we first investigated the effect of phosphorus deficiency on the formation of nonmotile cells of H. pluvialis, and then investigated the effect of NaCl on the formation of nonmotile cells under the conditions of phosphorus deficiency. The results showed that, after three days of treatment with 0.1% NaCl under phosphorus deficiency, more than 80% of motile cells had been transformed into nonmotile cells. The work provides the most efficient method for the cultivation of H. pluvialis nonmotile cells so far, and it significantly improves the production of H. pluvialis astaxanthin.