文献类型：期刊文献

中文题名：间歇低氧运动对肥胖大鼠食欲的影响及其机制分析

英文题名：Analysis of the effect of intermittent hypoxic exercising on the appetite of obese rats and its mechanism

作者：陈瑜文[1];林文弢[2];邱烈峰[3];翁锡全[2]

机构：[1]广东海洋大学体育与休闲学院;[2]广州体育学院省重点生化实验室;[3]信阳师范学院体育学院

年份：2011

卷号：18

期号：4

起止页码：133

中文期刊名：体育学刊

外文期刊名：Journal of Physical Education

收录：CSTPCD、、国家哲学社会科学学术期刊数据库、北大核心2008、CSSCI2010_2011、北大核心、CSSCI

语种：中文

中文关键词：运动生物化学;食欲;间歇低氧运动;肥胖大鼠

外文关键词：exercise biochemistry; appetite; intermittent hypoxic exercising; obese rat

中文摘要：探讨间歇低氧运动对营养性肥胖SD大鼠摄食的影响并分析其可能机制,为间歇低氧减肥提供理论依据。为此,通过对雄性SD大鼠饲喂高脂饲料建立营养性肥胖模型,然后进行为期4周的间歇低氧运动(运动速度为20 m/min,?(O2)前2周为15.4%,后2周为14.5%)。间歇低氧运动组进行4周间歇低氧运动刺激。结果发现:与常氧安静组相比,常氧运动组和间歇低氧运动组肥胖SD大鼠下丘脑瘦素和瘦素受体含量增加(常氧运动组P<0.05,间歇低氧运动组P<0.01),大鼠的每日摄食量减少。与常氧运动组相比,间歇低氧运动组肥胖SD大鼠下丘脑瘦素和瘦素受体含量增加(瘦素P<0.05,瘦素受体P<0.01)。结果说明:1)间歇低氧运动抑制了肥胖大鼠的食欲,减少了摄食量,减缓了大鼠体重的增加,并且间歇低氧效果比单纯运动效果好;2)间歇低氧运动抑制大鼠食欲可能与大鼠下丘脑瘦素和瘦素受体含量增加,进而抑制神经肽Y有关。

外文摘要：The authors probed into the effect of intermittent hypoxic exercising on the ingestion of nutritional obese SD rats,so as to provide a theoretical criterion for weight reduction through intermittent hypoxic exercising.Hence,the authors established a nutritional obesity model for feeding male SD rats with high fat feed,then let the rats in the intermittent hypoxic exercising group do a 4-week intermittent hypoxic exercise（exercising speed： 20 m/min,（O2）： 15.4% in the first two weeks,14.5% in the last two weeks）,and revealed the following findings： as com-pared with the rats in the normoxic calm group,the contents of hypothalamus leptins and leptin receptors of obese SD rats in the normoxic exercising group and intermittent hypoxic exercising group increased（the rats in the nor-moxic exercising group： P0.05,the rats in the intermittent hypoxic exercising group： P0.01）,and the daily inges-tion of the rats decreased;as compared with the rats in the normoxic exercising group,the contents of hypothalamus leptins and leptin receptors of obese SD rats in the intermittent hypoxic exercising group increased（leptins： P0.05,leptin receptors： P0.01）.The findings indicated the followings： 1） intermittent hypoxic exercising restrained the appetite of obese rats,reduced their ingestion,and slowed down the increase of their weight;the effect of intermit-tent hypoxic exercising was better than the effect of simple exercising;2） intermittent hypoxic exercising restraining the appetite of the rats may be related to the restraining of neuropeptide Y as a result of the increase of the contents of hypothalamus leptins and leptin receptors of the rats.