文献类型：期刊文献

英文题名：Dietary lipid levels affected growth performance, lipid accumulation, inflammatory response and apoptosis of japanese seabass (lateolabrax japonicus)

作者：Xie, Shiwei[1,2,3];Lin, YingYing[1];Wu, Tao[4];Tian, Lixia[4];Liang, Jianjun[5];Tan, Beiping[1,2,3]

机构：[1]Guangdong Ocean Univ, Fisheries Coll, Lab Aquat Anim Nutr & Feed, Zhanjiang, Peoples R China;[2]Aquat Anim Precis Nutr & High Efficiency Feed Eng, Zhanjiang 524088, Peoples R China;[3]Minist Agr, Key Lab Aquat Livestock & Poultry Feed Sci & Tecn, Zhanjiang 524088, Peoples R China;[4]Sun Yat Sen Univ, Inst Aquat Econ Anim, Sch Life Sci, Guangdong Prov Key Lab Improved Variety Reprod Aq, Guangzhou, Peoples R China;[5]Zhuhai Dehai Biol Technol Co Ltd, Zhuhai, Guangdong, Peoples R China

年份：2021

卷号：27

期号：3

起止页码：807

外文期刊名：AQUACULTURE NUTRITION

收录：SCI-EXPANDED(收录号：WOS:000608162700001)、、WOS

基金：Agriculture Science and Technology Project of Zhuhai Doumen District, Grant/Award Number: 2018110809

语种：英文

外文关键词：apoptosis; high-fat diet; inflammation response; Japanese seabass; lipid metabolism; lipid requirement

外文摘要：An eight weeks feeding trial was conducted to investigate the effects of dietary lipid levels on growth performance, lipid metabolism and immune response of Japanese seabass (Lateolabrax japonicus). Five diets were formulated with gradient dietary lipid levels (79.6, 104.4, 129.1, 154.9 and 178.6 g kg(-1)). Results revealed that growth and feed utilization of fish were significantly lower in group L178.6 than other groups (p < 0.05). Lipid accumulation in whole body, muscle and intraperitoneal were increased with increasing dietary lipid levels. The mRNA levels of adipose triglyceride lipase, carnitine palmitoyl transferase 1, acetyl CoA carboxylase, cholesterol 7 alpha-hydroxylase and retinoid X receptor in liver were also increased with increasing dietary lipid levels (p < 0.05). The mRNA levels of apolipoprotein A1 and peroxisome proliferator activating receptor alpha were higher in fish fed L178.6 than those fed other diets. Oxidative stress in plasma and liver were induced when dietary lipid exceed 154.9 g kg(-1). L154.9 and L178.6 significantly increased the inflammatory related gene expression of fish. These results suggested that high-fat diet impaired the growth performance and induced lipid accumulation, inflammation and apoptosis of Japanese seabass. The suitable dietary lipid level of Japanese seabass may not exceed 129.1 g kg(-1).