文献类型：期刊文献

英文题名：Conservation of Endangered Cordyceps sinensis Through Artificial Cultivation Strategies of C. militaris, an Alternate

作者：Krishna, Kondapalli Vamsi[1];Balasubramanian, Balamuralikrishnan[2];Park, Sungkwon[2];Bhattacharya, Sukanta[1];Sebastian, Joseph Kadanthottu[3];Liu, Wen-Chao[4];Pappuswamy, Manikantan[3];Meyyazhagan, Arun[3];Kamyab, Hesam[5,6];Chelliapan, Shreeshivadasan[7];Malaviya, Alok[1,8]

机构：[1]CHRIST Univ, Appl & Ind Biotechnol Lab, Hosur Rd, Bangalore, Karnataka, India;[2]Sejong Univ, Coll Life Sci, Dept Food Sci & Biotechnol, Seoul, South Korea;[3]CHRIST Univ, Dept Life Sci, Bangalore, Karnataka, India;[4]Guangdong Ocean Univ, Coll Coastal Agr Sci, Dept Anim Sci, Zhanjiang 524088, Peoples R China;[5]Saveetha Inst Med & Tech Sci, Saveetha Dent Coll & Hosp, Dept Biomat, Chennai 600077, India;[6]Univ Relig & Denominat, Fac Social Sci Media & Commun, Qom, Iran;[7]Univ Teknol Malaysia, Fac Artificial Intelligence, Dept Smart Engn & Adv Technol, Kuala Lumpur 54100, Malaysia;[8]QuaLife Biotech Pvt Ltd, Bangalore, India

年份：2024

外文期刊名：MOLECULAR BIOTECHNOLOGY

收录：SCI-EXPANDED(收录号：WOS:001207690800003)、、EI(收录号：20241816003469)、Scopus(收录号：2-s2.0-85191300423)、WOS

基金：Kondapalli Vamsi Krishna would acknowledge the fellowship from KSTePS, Department of Science and Technology (DST), Govt. of Karnataka for fellowship to pursue his PhD work.

语种：英文

外文关键词：Cordyceps sinensis; Cordyceps militaris; Sustainability; Solid state fermentation; Liquid culture

外文摘要：Cordyceps, an entomopathogenic fungus belonging to the Ascomycota phylum, is a familiar remedial mushroom that is extensively used in the traditional medicinal system, especially in South Asian nations. The significance of this genus' members in a range of therapeutic and biotechnological applications has long been acknowledged. The exceedingly valuable fungus Ophiocordyceps sinensis (Cordyceps sinensis) is found in the alpine meadows of Bhutan, Nepal, Tibet, and India, where it is severely harvested. Driven by market demand and ecological concerns, the study highlights challenges in natural C. sinensis collection and emphasizes the shift towards sustainable artificial cultivation methods. This in-depth review navigates Cordyceps cultivation strategies, focusing on C. sinensis and the viable alternative, C. militaris. The escalating demand for Cordyceps fruiting bodies and bioactive compounds prompts a shift toward sustainable artificial cultivation. While solid-state fermentation on brown rice remains a traditional method, liquid culture, especially submerged and surface/static techniques, emerges as a key industrial approach, offering shorter cultivation periods and enhanced cordycepin production. The review accentuates the adaptability and scalability of liquid culture, providing valuable insights for large-scale Cordyceps production. The future prospects of Cordyceps cultivation require a holistic approach, combining scientific understanding, technological innovation, and sustainable practices to meet the demand for bioactive metabolites while ensuring the conservation of natural Cordyceps populations.