文献类型：期刊文献

英文题名：Effects of dietary vitamin E on growth, immunity and oxidation resistance related to the Nrf2/Keap1 signalling pathway in juvenile Sillago sihama

作者：Huang, Qin-Cheng[1,2,3];Zhang, Shuang[1,2,3];Du, Tao[4];Yang, Qi-Hui[1,2,3];Chi, Shu-Yan[1,2,3];Liu, Hong-Yu[1,2,3];Yang, Yuan-Zhi[1];Dong, Xiao-Hui[1,2,3];Tan, Bei-Ping[1,2,3]

机构：[1]Guangdong Ocean Univ, Coll Fisheries, Lab Aquat Nutr & Feed, Zhanjiang 524025, Peoples R China;[2]Aquat Anim Precis Nutr & High Efficiency Feed Eng, Zhanjiang 524025, Peoples R China;[3]Minist Agr, Key Lab Aquat Livestock & Poultry Feed Sci & Tech, Zhanjiang 524000, Guangdong, Peoples R China;[4]Guangdong Ocean Univ Marine Biol Res Base, Zhanjiang 524072, Peoples R China

年份：2020

卷号：262

外文期刊名：ANIMAL FEED SCIENCE AND TECHNOLOGY

收录：SCI-EXPANDED(收录号：WOS:000522387100013)、、WOS

基金：We are grateful for the support of the Science and Technology Department of Guangdong Province (2015A020209170), Marine and Fisheries Department of Guangdong Province (A201608C06), Science and Technology Bureau of Zhanjiang (2016A3022), Graduate education innovation program of Guangdong Ocean University (201834) and China Agriculture Research System (CARS-47).

语种：英文

外文关键词：Antioxidant; Growth promotion; Immunity; Nrf2/Keap1 signal molecules; Sillagosihama; Vitamin E

外文摘要：The influence of dietary vitamin E supplementation on growth, immunity and oxidation resistance related to nuclear factor-erythroid 2-related factor 2 (Nrf2)/Kelch-like epichlorohydrin associating protein 1 (Keap1) signalling molecules in juvenile Sillago sihama (2.14 +/- 0.02 g, initial mean weight +/- SD) was investigated. Altogether, 720 fish were divided into six groups with four repetitions (30 fish each) and fed six diets containing graded concentrations of vitamin E including 4, 14, 22, 47, 95 and 198 mg/kg respectively for eight weeks. Compared with the control, results suggested that dietary vitamin E had the following effects: increased weight gain rate (WG), protein efficiency ratio (PER) and feed intake (FI), and decreased feed conversion ratio (FCR) (P < 0.05); increased hepatic alkaline phosphatase (AKP) activity, complement 3 (C3) and immunoglobulin M (IgM) concentrations (P < 0.05); increased glutathione-S-transferase (GST), catalase (CAT) and glutathione peroxidase (GPx) activities; decreased malondialdehyde (MDA) concentration in the liver; increased copper-zinc superoxide dismutase (CuZnSOD), GST, CAT and GPx activities in the intestine (P < 0.05); and upregulated Nrf2, Keap1, CAT, GST, GPx, glutathione reductase (GR), CuZnSOD and manganese superoxide dismutase (MnSOD) gene expression in the liver and intestine (P < 0.05). Based on regression analysis for WG, the dietary requirement of vitamin E for juvenile S. sihama was estimated to be 100.37 mg/kg.