文献类型：期刊文献

英文题名：Transcriptomic responses reveal impaired physiological performance of the pearl oyster following repeated exposure to marine heatwaves

作者：He, Guixiang[1];Xiong, Xinwei[1];Peng, Yalan[2];Yang, Chuangye[1];Xu, Yang[1];Liu, Xiaolong[1];Liang, Jian[1];Masanja, Fortunatus[1];Yang, Ke[1];Xu, Xin[1];Zheng, Zhe[1];Deng, Yuewen[1];Leung, Jonathan Y. S.[3];Zhao, Liqiang[1]

机构：[1]Guangdong Ocean Univ, Fisheries Coll, Zhanjiang 524088, Peoples R China;[2]Minist Nat Resources, Zhuhai Cent Stn Marine Environm Monitoring, Zhuhai 519015, Peoples R China;[3]Univ Adelaide, Sch Biol Sci, Southern Seas Ecol Labs, Adelaide, SA 5005, Australia

年份：2023

卷号：854

外文期刊名：SCIENCE OF THE TOTAL ENVIRONMENT

收录：SCI-EXPANDED(收录号：WOS:000930944200009)、、EI(收录号：20223812762562)、Scopus(收录号：2-s2.0-85138118839)、WOS

基金：The present study has been made possible by research grants from the Sci- ence and Technology Program of Guangdong Province (2021B0202020003) , the National Science Foundation of China (42076121, 42176199, M-0163) , the Department of Education of Guangdong Province (2020KTSCX050) , and the earmarked fund for Modern Agro-industry Technology Research System (CARS -49) .

语种：英文

外文关键词：Climate change; Extreme weather event; Marine heatwave; Physiological process; Gene expression; Bivalve

外文摘要：Marine heatwaves are predicted to become more intense and frequent in the future, possibly threatening the survival of marine organisms and devastating their communities. While recent evidence reveals the adaptability of marine or-ganisms to heatwaves, substantially overlooked is whether they can also adjust to repeated heatwave exposure, which can occur in nature. By analysing transcriptome, we examined the fitness and recoverability of the pearl oyster (Pinctada maxima) after two consecutive heatwaves (24 degrees C to 32 degrees C for 3 days; recovery at 24 degrees C for 4 days). In the first heatwave, 331 differentially expressed genes (DEGs) were found, such as AGE-RAGE, MAPK, JAK-STAT, FoxO and mTOR. Despite the recovery after the first heatwave, 2511 DEGs related to energy metabolism, body defence, cell proliferation and biomineralization were found, where 1655 of them were downregulated, suggesting a strong negative response to the second heatwave. Our findings imply that some marine organisms can indeed tolerate heatwaves by boosting energy metabolism to support molecular defence, cell proliferation and biomineralization, but this capacity can be overwhelmed by repeated exposure to heatwaves. Since recurrence of heatwaves within a short period of time is predicted to be more prevalent in the future, the functioning of marine ecosystems would be disrupted if marine organisms fail to accommodate repeated extreme thermal stress.