文献类型：期刊文献

中文题名：岩藻多糖对断奶羔羊生长性能、器官指数及血清生化、抗氧化和免疫指标的影响

英文题名：Effects of Fucoidan on Growth Performancerum Biochemical,Organ Indices and Se,Antioxidant and Immune Indices of Weaned Lambs

作者：郭广振[1];杨伟光[1];刘娟[1];陈佳怡[1];王胜男[1];尹福泉[1];冯钰晴[1];高振华[1]

机构：[1]广东海洋大学滨海农业学院,湛江524088

年份：2022

卷号：34

期号：5

起止页码：3122

中文期刊名：动物营养学报

外文期刊名：CHINESE JOURNAL OF ANIMAL NUTRITION

收录：CSTPCD、、CSCD2021_2022、北大核心、CSCD、北大核心2020

基金：广东省农业农村厅项目——广东省现代草牧业(羊)产业技术体系(2019KJ127);2019年广东省科技厅项目——雷州山羊健康养殖技术集成(K19015);广东省科技专项资金(“大专项”+“任务清单”)项目——雷州山羊保育繁推一体化生态健康养殖关键技术创新与示范项目;华南农业大学-广东海洋大学高校服务乡村振兴共同体黑山羊养殖协同服务项目;2020年国家级大创项目——宏组学分析岩藻多糖介导瘤胃微生物对雷州山羊免疫调控机理研究(580520011)。

语种：中文

中文关键词：岩藻多糖;早期断奶羔羊;血清生化;抗氧化;免疫

外文关键词：fucoidan;early-weaned lambs;serum biochemical;antioxidant;immune

中文摘要：本试验旨在探讨岩藻多糖对断奶羔羊生长性能、器官指数及血清生化、抗氧化和免疫指标的影响。选择24只体重[(7.32±0.37) kg]相近的30日龄健康川中黑山羊公羔,随机分为4组,每组6个重复,每个重复1只。Ⅰ组(对照组)饲喂不含岩藻多糖的代乳粉,Ⅱ组、Ⅲ组、Ⅳ组分别在代乳粉中添加0.1%、0.3%、0.6%的岩藻多糖。预试期7 d,正试期30 d。结果表明:1)Ⅲ组和Ⅳ组的第30天体重显著高于Ⅱ组(P<0.05)。第1~30天,Ⅱ组、Ⅲ组和Ⅳ组的平均日增重显著高于Ⅰ组(P<0.05),Ⅲ组的开食料采食量显著高于Ⅰ组和Ⅱ组(P<0.05),各组之间的代乳粉采食量差异不显著(P>0.05)。2)Ⅱ组、Ⅲ组和Ⅳ组的脾脏指数显著高于Ⅰ组(P<0.05)。3)Ⅳ组的血清球蛋白(GLB)含量显著高于Ⅰ组(P <0.05),Ⅲ组和Ⅳ组的血清碱性磷酸酶(AKP)活性显著高于Ⅰ组和Ⅱ组(P <0.05)。4)Ⅱ组、Ⅲ组和Ⅳ组的血清总抗氧化能力(T-AOC)和谷胱甘肽过氧化物酶(GSH-Px)活性显著高于Ⅰ组(P<0.05),Ⅲ组和Ⅳ组的血清过氧化氢酶(CAT)活性显著高于Ⅰ组和Ⅱ组(P<0.05),Ⅲ组的血清超氧化物歧化酶(SOD)活性显著高于Ⅰ组、Ⅱ组和Ⅳ组(P<0.05),Ⅱ组、Ⅲ组和Ⅳ组的血清丙二醛(MDA)含量显著低于Ⅰ组(P<0.05)。5)Ⅲ组的血清免疫球蛋白G(IgG)含量显著高于Ⅰ组和Ⅱ组(P<0.05),Ⅱ组、Ⅲ组和Ⅳ组的血清免疫球蛋白M(IgM)含量显著低于Ⅰ组(P<0.05),Ⅲ组和Ⅳ组的血清白细胞介素-1β(IL-1β)和肿瘤坏死因子-α(TNF-α)含量显著低于Ⅰ组和Ⅱ组(P<0.05),Ⅲ组和Ⅳ组的血清白细胞介素-10(IL-10)含量显著高于Ⅰ组和Ⅱ组(P<0.05)。综上所述,代乳粉中添加岩藻多糖能够改善断奶羔羊的血清生化指标,提高生长性能、抗氧化能力和免疫性能。本试验条件下,代乳粉中岩藻多糖的适宜添加量为0.3%。

外文摘要：This experiment was conducted to determine the effects of fucoidan on growth performance,organ indices and serum biochemical,antioxidant and immune indices of weaned lambs. Twenty-four healthy 30-dayold Chuanzhong black male lambs with similar body weight of(7.32±0.37)kg were randomly divided into 4groups with 6 replicates per group and 1 lamb per replicate. Lambs in groupⅠ (control group)were fed the milk replacer without fucoidan,and others in groupⅡ,groupⅢand groupⅣwere milk replacers supplemented with 0.1%,0.3% and 0.6% fucoidan,respectively. The pre-experimental period lasted for 7 days,and the experimental period lasted for 30 days. The results showed as follows:1)the body weight at day 30 of groupⅢand groupⅣwas significantly higher than that of groupⅡ (P<0.05). During days 1 to 30,the average daily gain of groupⅡ,groupⅢand groupⅣwas significantly higher than that of groupⅠ (P<0.05),the starter intake of groupⅢwas significantly higher than that of groupⅠand groupⅡ (P<0.05),and there was no significant difference in milk replacer intake among all groups(P>0.05). 2)The spleen index of groupⅡ,groupⅢand groupⅣwas significantly higher than that of groupⅠ (P<0.05). 3)The serum globulin(GLB)content of groupⅣwas significantly higher than that of groupⅠ (P<0.05),and the serum alkaline phosphatase(AKP)activity of groupⅢand groupⅣwas significantly higher than that of groupⅠand groupⅡ (P<0.05). 4)The serum total antioxidant capacity(T-AOC)and glutathione peroxidase(GSH-Px)activity of groupⅡ,groupⅢand groupⅣwere significantly higher than those of groupⅠ (P<0.05),the serum catalase(CAT)activity of groupⅢand groupⅣwas significantly higher than that of groupⅠand groupⅡ(P<0.05),the serum superoxide dismutase(SOD)activity of groupⅢwas significantly higher than that of groupⅠ,groupⅡand groupⅣ (P<0.05),and the serum malondialdehyde(MDA)content of groupⅡ,groupⅢand groupⅣwas significantly lower than that of groupⅠ (P<0.05). 5)The serum immunoglobulin G(IgG)content of groupⅢwas significantly higher than that of groupⅠand groupⅡ (P<0.05),the serum immunoglobulin M(IgM)content of groupⅡ,groupⅢand groupⅣwas significantly lower than that of groupⅠ (P<0.05),the contents of interleukin-1β(IL-1β)and tumor necrosis factor-α(TNF-α)in serum of groupⅢand groupⅣwere significantly lower than those of groupⅠand groupⅡ (P<0.05),and the serum interleukin-10(IL-10)of groupⅢand groupⅣwas significantly higher than that of groupⅠand groupⅡ (P<0.05). In conclusion,adding fucoidan in milk replace can improve serum biochemical indices,growth performance,antioxidant capacity and immune performance of weaned lambs. Under the experimental conditions,the appropriate addition of fucoidan in milk replacer is 0.3%.[Chinese Journal of Animal Nutrition,2022,34(5):3122-3131]