文献类型：期刊文献

英文题名：The current status and development forecasts of vaccines for aquaculture and its effects on bacterial and viral diseases

作者：Mkulo, Evodia Moses[1,2,3];Wang, Bei[1,4,5,6];Amoah, Kwaku[1,4,5,6];Huang, Yu[1,4,5,6];Cai, Jia[1,4,5,6];Jin, Xiao[1,4,5,6];Wang, Zhongliang[1,2,3,4,7]

机构：[1]Guangdong Ocean Univ, Coll Fisheries, Zhanjiang 524088, Peoples R China;[2]Southern Marine Sci & Engn Guangdong Lab, Zhanjiang 524025, Peoples R China;[3]Guangdong Prov Key Lab Pathogen Biol & Epidemiol A, Zhanjiang 524088, Peoples R China;[4]Guangdong Ocean Univ, Guangdong Prov Key Lab Aquat Anim Dis Control & Hl, Zhanjiang 524088, Peoples R China;[5]Southern Marine Sci & Engn Guangdong Lab, Key Lab Control Dis Aquat Anim Guangdong Higher Ed, Zhanjiang, Peoples R China;[6]Guangdong Prov Engn Res Ctr Aquat Anim Hlth Assess, Shenzhen 327005, Peoples R China;[7]Agrotech Extens Ctr Guangdong Prov, Guangzhou, Peoples R China

年份：2024

卷号：196

外文期刊名：MICROBIAL PATHOGENESIS

收录：SCI-EXPANDED(收录号：WOS:001327975500001)、、WOS

基金：The research leading to these results was financially supported by the Program for Scientific Research Start-up funds of Guangdong Ocean University (060302022310) , the Guangdong Provincial Key Special Program for Ordinary Colleges and Universities (2023ZDZX4011) , the Key Scientific Research Platforms and Projects of ordinary Universities in Guangdong Province (2021KCXTD026; 2022KCXTD013) , the Research on breeding technology of candidate species for Guangdong modern marine ranching (2024-MRB-00-001) , and the Zhuhai Science and Technology Plan Projects in the Field of Social Development (2320004001603) .r Research on breeding technology of candidate species for Guangdong modern marine ranching (2024-MRB-00-001) , and the Zhuhai Science and Technology Plan Projects in the Field of Social Development (2320004001603) .

语种：英文

外文关键词：Aquaculture sustainability; Bacteria diseases Immunity; Infectious pancreatic necrosis virus (IPNV); Nanoparticle-based vaccine; Nanoparticle-based vaccine

外文摘要：The aquaculture sector predicts protein-rich meals by 2040 and has experienced significant economic shifts since 2000. However, challenges emanating from disease control measures, brood stock improvement, feed advancements, hatchery technology, and water quality management due to environmental fluctuations have been taken as major causative agents for hindering the sector's growth. For the past years, aquatic disease prevention and control have principally depended on the use of various antibiotics, ecologically integrated control, other immunoprophylaxis mechanisms, and chemical drugs, but the long-term use of chemicals such as antibiotics not only escalates antibiotic-resistant bacteria and genes but also harms the fish and the environments, resulting in drug residues in aquatic products, severely obstructing the growth of the aquaculture sector. The field of science has opened new avenues in basic and applied research for creating and producing innovative and effective vaccines and the enhancement of current vaccines to protect against numerous infectious diseases. Recent advances in vaccines and vaccinology could lead to novel vaccine candidates that can tackle fish diseases, including parasitic organism agents, for which the current vaccinations are inadequate. In this review, we study and evaluate the growing aquaculture production by focusing on the current knowledge, recent progress, and prospects related to vaccinations and immunizations in the aquaculture industry and their effects on treating bacterial and viral diseases. The subject matter covers a variety of vaccines, such as conventional inactivated and attenuated vaccines as well as advanced vaccines, and examines their importance in real-world aquaculture scenarios. To encourage enhanced importation of vaccines for aquaculture sustainability and profitability and also help in dealing with challenges emanating from diseases, national and international scientific and policy initiatives need to be informed about the fundamental understanding of vaccines.