文献类型：期刊文献

英文题名：Fucoidan-Derived Functional Oligosaccharides: Recent Developments, Preparation, and Potential Applications

作者：Wang, Min[1,2];Veeraperumal, Suresh[3];Zhong, Saiyi[1];Cheong, Kit-Leong[3]

机构：[1]Guangdong Ocean Univ, Coll Food Sci & Technol, Guangdong Prov Engn Technol Res Ctr Seafood,Guangd, Guangdong Prov Sci & Technol Innovat Ctr Subtrop F, Zhanjiang 524088, Peoples R China;[2]Guangdong Ocean Univ, Postgrad Coll, Zhanjiang 524088, Peoples R China;[3]Shantou Univ, Dept Biol, Shantou 515063, Peoples R China

年份：2023

卷号：12

期号：4

外文期刊名：FOODS

收录：SCI-EXPANDED(收录号：WOS:000945185000001)、、Scopus(收录号：2-s2.0-85148907987)、WOS

基金：This work was supported in part by the Key-Area Research and Development Program of Guangdong Province (2020B1111030004), The Innovative Team Program of High Education of Guangdong Province (2021KCXTD021), and The Program for Scientific Research Start-up Funds of Guangdong Ocean University (2023).

语种：英文

外文关键词：fuco-oligosaccharides; brown algae; preparation; biological activities; prebiotics

外文摘要：Oligosaccharides derived from natural resources are attracting increasing attention as both food and nutraceutical products because of their beneficial health effects and lack of toxicity. During the past few decades, many studies have focused on the potential health benefits of fucoidan. Recently, new interest has emerged in fucoidan, partially hydrolysed into fuco-oligosaccharides (FOSs) or low-molecular weight fucoidan, owing to their superior solubility and biological activities compared with fucoidan. There is considerable interest in their development for use in the functional food, cosmetic, and pharmaceutical industries. Therefore, this review summarises and discusses the preparation of FOSs from fucoidan using mild acid hydrolysis, enzymatic depolymerisation, and radical degradation methods, and discusses the advantages and disadvantages of hydrolysis methods. Several purification steps performed to obtain FOSs (according to the latest reports) are also reviewed. Moreover, the biological activities of FOS that are beneficial to human health are summarised based on evidence from in vitro and in vivo studies, and the possible mechanisms for the prevention or treatment of various diseases are discussed.