文献类型：期刊文献

英文题名：Concern regarding H3-subtype avian influenza virus

作者：Yu, Jiantao[1];Yao, Qiucheng[1];Liu, Jing[1];Zhou, Yan[1];Huo, Miaotong[1];Ge, Ye[1]

机构：[1]Guangdong Ocean Univ, Coll Coastal Agr Sci, Zhanjiang, Peoples R China

年份：2023

卷号：14

外文期刊名：FRONTIERS IN MICROBIOLOGY

收录：SCI-EXPANDED(收录号：WOS:001127682700001)、、Scopus(收录号：2-s2.0-85180265780)、WOS

基金：The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Natural Resource Affairs (Ecological Forestry Construction) Project of the Guangdong Forestry Department (grant number K23051), the Innovation and Strengthening Project of Guangdong Ocean University (grant number 230419067), and a Ph.D. start-up grant (grant number 521202292).

语种：英文

外文关键词：avian influenza virus; H3-subtype; genetics; evolution; interspecies transmission

外文摘要：The H3-subtype of avian influenza virus (AIV) is one of the most frequently detected low pathogenic avian influenza virus (LPAIV) subtypes in birds and fowls, causing substantial economic loss to the poultry industry. Most importantly, besides poultry, mammals could also be infected with it, such as swines, canines, equines, felines, and humans, posing a serious public health threat. This allows the virus to persist widely in poultry and wild birds for a long time, where it may mix with other subtypes, providing conditions for viral recombination or reassortment. Currently, the monitoring of H3-subtype AIV is inadequate, and there is a lack of effective prevention and control measures for H3-subtype AIV. Here, the epidemiology, phylogeny, and genetic variation of H3-subtype AIV were analyzed, and nonsynonymous and synonymous substitution rates (dN/dS) were calculated. Through these steps, we aimed to clarify the current epidemiological feature and evolutionary characteristics of H3-subtype AIV, and provide an operative reference for future scientific control of H3-subtype AIV.