文献类型：期刊文献

英文题名：Role of microRNAs in myogenesis and their effects on meat quality in pig - A review

作者：Iqbal, Ambreen[1];Jiang Ping[1];Ali, Shaokat[1];Gao Zhen[1];Liu Juan[1];Jin Zi Kang[1];Pan Ziyi[1];Lu Huixian[1];Zhao Zhihui[1]

机构：[1]Guangdong Ocean Univ, Coll Coastal Agr Sci, Dept Anim Breeding & Genet, Zhanjiang 524088, Guangdong, Peoples R China

年份：2020

卷号：33

期号：12

起止页码：1873

外文期刊名：ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES

收录：SCI-EXPANDED(收录号：WOS:000582676900001)、、Scopus(收录号：2-s2.0-85095591187)、WOS

基金：This work was supported by the National Natural Science Foundation of China (No.31772562), The youth Project of Innovative Strong School Engineering by the Department of Education of Guangdong Province (2019KQNCX042), and the Key Platform Project of Innovative Strong School Engineering by the Department of Education of Guangdong Province (2018302).

语种：英文

外文关键词：microRNA; Myogenesis; Meat Quality; Pig

外文摘要：The demand for food is increasing day by day because of the increasing global population. Therefore, meat, the easiest and largely available source of protein, needs to be produced in large amounts with good quality. The pork industry is a significant shareholder in fulfilling the global meat demands. Notably, myogenesis-development of muscles during embryogenesis-is a complex mechanism which culminates in meat production. But the molecular mechanisms which govern the myogenesis are less known. The involvement of miRNAs in myogenesis and meat quality, which depends on factors such as myofiber composition and intramuscular fat contents which determine the meat color, flavor, juiciness, and water holding capacity, are being extrapolated to increase both the quantity and quality of pork. Various kinds of microRNAs (miRNAs), miR-1, miR-21, miR22, miR-27, miR-34, miR-127, miR-133, miR-143, miR-155, miR-199, miR-206, miR-208, miR-378, and miR-432 play important roles in pig skeletal muscle development. Further, the quality of meat also depends upon myofiber which is developed through the expression of different kinds of miRNAs at different stages. This review will focus on the mechanism of myogenesis, the role of miRNAs in myogenesis, and meat quality with a focus on the pig.