文献类型：期刊文献

英文题名：From Molecular Assembly to Biological Function: An Ovalbumin-Fucoidan Complex Stabilized Emulsion for Enhancing the Antioxidant Efficacy of Galangin

作者：Wang, Yitong[1,2,3,4,5]; Wang, Rui[1,2,3,4,5]; Guo, Qiaoying[1,2,3,4,5]; Xu, Xiaoqian[1,2,3,4,5]; Teng, Hui[1,2,3,4,5]; Chen, Lei[1,2,3,4,5,6]; Zhao, Yanan[1,2,3,4,5,6]

机构：[1] College of Food Science and Technology, Guangdong Ocean University, Guangdong, Zhanjiang, 524000, China; [2] Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Guangdong, Zhanjiang, 524000, China; [3] Guangdong Province Engineering Laboratory for Marine Biological Products, Guangdong, Zhanjiang, 524000, China; [4] Guangdong Provincial Engineering Technology Research Center of Seafood, Guangdong, Zhanjiang, 524000, China; [5] Key Laboratory of Advanced Processing of Aquatic Product of Guangdong Higher Education Institution, Guangdong, Zhanjiang, 524000, China; [6] Shenzhen Institute of Guangdong Ocean University, Shenzhen, 518108, China

年份：2025

外文期刊名：SSRN

收录：EI(收录号：20250537329)

语种：英文

外文关键词：Antioxidants - Hydrogen bonds - Hydrophobicity - Oxidative stress - Particle size - Particle size analysis

外文摘要：This study focused on a novel binary complex formed between ovalbumin (OVA) and fucoidan (FUC) via hydrogen bonding and hydrophobic interactions. The mechanism and emulsifying properties of the OVA-FUC complex were systematically explored by varying FUC content. The structural changes of the OVA-FUC emulsion during formation and storage were investigated by analyzing the microstructure, zeta potential, and particle size, and the functionality of the emulsion was further investigated. The results indicated that the OVA-FUC complex effectively stabilized the emulsion, with the encapsulated galangin (GAL) showing high retention and minimal degradation during storage. Evaluated through a combination of in vitro assays (DPPH and ABTS) and an in vivo C. elegans model of EtOH-induced oxidative stress, emulsion loaded with GAL exhibited significant antioxidant efficacy, thereby conferring protection and enhancing survival rates under oxidative challenge. ? 2025, The Authors. All rights reserved.