文献类型：期刊文献

中文题名：壳聚糖及其衍生物抗菌活性的研究进展

英文题名：Research Progress on Atibacterial Ativity of Citosan and Its Drivatives

作者：梁丽媚[1];李思东[1];李程鹏[1];侯婷婷[1]

机构：[1]广东海洋大学化学与环境学院,广东湛江524088

年份：2017

卷号：45

期号：20

起止页码：6

中文期刊名：广州化工

外文期刊名：GuangZhou Chemical Industry

基金：广东省科技计划项目(No:2015A020216019);广东省科技计划项目(No:2017A010103023);广东省高等学校科技创新项目(No:GDOU2016050255)

语种：中文

中文关键词：壳聚糖;抗菌机理;衍生物;抗菌活性

外文关键词：chitosan; antibacterial mechanism; derivatives; antibacterial activity

中文摘要：壳聚糖资源丰富,无毒,且具有生物相容性和生物可降解性以及优良的抗菌性能等,因此具有广泛的应用前景。21世纪以来,壳聚糖及其衍生物作为新型抗菌剂受到人们的重视,研究发现其可能的抗菌机理主要是:破坏细菌细胞壁、损坏细菌DNA功能和抑制菌体对微量元素的摄取。本文综述了近年来壳聚糖及其衍生物的抗菌活性情况,并针对其机理和研究进展进行了深刻的讨论。

外文摘要：Due to its abundant availability,non-toxicity,biocompatibility,biodegradability and superior antibacterial activity,chitosan possesses broad application prospects in various areas.Since twenty-first Century,chitosan and its derivatives have attracted more and more attention as a new kind of antibacterial agents.It is found that the possible antibacterial mechanism of chitosan and its derivatives can be summarized as three perspectives.Research shows that the antibacterial mechanism of chitosan may be due to its damages to cell walls and DNA functions,and its inhabitation on the bacteria＇s uptake of trace elements.The antibacterial activity of chitosan and its derivatives in recent years were reviewed in-depth,providing a comprehensive survey and assessment of their mechanisms and advances.