文献类型：期刊文献

英文题名：Current research and future perspectives of GH and IGFs family genes in somatic growth and reproduction of teleost fish

作者：Ndandala, Charles Brighton[1,2];Dai, Mingshu[1];Mustapha, Umar Farouk[1];Li, Xiaomeng[1];Liu, Jinlei;Huang, Hai[3];Li, Guangli[1];Chen, Huapu[1,2,4]

机构：[1]Guangdong Ocean Univ, Fisheries Coll, Guangdong Res Ctr Reprod Control & Breeding Techno, Guangdong Prov Key Lab Pathogen Biol & Epidemiol A, Zhanjiang 524088, Peoples R China;[2]Southern Marine Sci & Engn Guangdong Lab Zhanjiang, Zhanjiang 524025, Peoples R China;[3]Hainan Trop Ocean Univ, Yazhou Bay Innovat Inst, Key Lab Utilizat & Conservat Trop Marine Bioresour, Minist Educ,Hainan Key Lab Conservat & Utilizat Tr, Sanya 572022, Peoples R China;[4]Guangdong Havwii Agr Grp co LTD, Zhanjiang 524266, Peoples R China

年份：2022

卷号：26

外文期刊名：AQUACULTURE REPORTS

收录：SCI-EXPANDED(收录号：WOS:000848326200002)、、Scopus(收录号：2-s2.0-85136556854)、WOS

基金：This article was supported by grants from the Key Research and Development Program of Guangdong (2021B202020002) , the National Natural Science Foundation of China (41706174, 32160861) , the Guangdong Basic and Applied Basic Research Foundation (2019A1515010958) , the talent team tender grant of Zhanjiang marine equipment and biology (2021E05035) , the Southern Marine Science and Engineering Guangdong Laboratory (Zhanjiang) (ZJW-2019-06) , and The Major Science and Technology plan of Hainan Province (ZDKJ2021017) .

语种：英文

外文关键词：IGF; Teleost fish; Somatic growth; Fasting; Oocyte maturation

外文摘要：The Growth hormone (GH)-insulin-like growth factors (IGFs) axis plays a central role as the endocrine regulator of physiological functions in teleost fish and other vertebrates. The basic mechanism of the GH-IGF system is well-known to be useful in a different manner, but it seems to operate differently between species. We have pointed out different aspects related to IGF family genes and their GH dependence that seems to vary according to species. We discussed the effects of nutritional status, and physiological functions of IGFs in teleost gonads to facilitate somatic growth as well as embryonic development and oocyte maturation regulation. We found that nutrients and diet composition are environmental factors that influence somatic growth. The effects of fasting and re-feeding serving as key factors in the expression of IGF genes in different tissues were briefly described, whereby we have found that prolonged fasting causes ceasing of growth but significant elevation of GH con-centration. Also, the IGFs have been reported to play significant roles in regulating both male and female gonad development. In addition, IGF3 is constantly expressed throughout all stages of embryogenesis. Therefore, improving our knowledge and understanding of these interactions will impact the design of better feeding intake and reproduction approaches to maximize growth performance, fish well-being, and maximum production of teleosts. This study is intended as a summary to provide the reader with a modern, and unique perspective on the past, present, and future of IGF research in teleosts. Therefore, we expect that gaps of knowledge will be exposed and stimulate future research areas related to IGFs in teleost fish with respect to growth and reproduction as well as other physiological functions.