文献类型：期刊文献

英文题名：Gut Microbiota Contributes To the Metabolic Function of Different Intestine Segments in Teleost

作者：Zhao, Na[1,2]; Yuan, Biao[2]; Lin, Jieyan[2]; Dong, Zhongdian[1]; Zhang, Bo[1,2]

机构：[1] College of Fishery, Guangdong Ocean University, Zhanjiang, 524088, China; [2] Southern Marine Science and Engineering Guangdong Laboratory [Zhanj iang], Zhanjiang, 524000, China

年份：2024

外文期刊名：SSRN

收录：EI(收录号：20240039158)

语种：英文

外文关键词：Ecology - Enzymes - Nutrients - Probiotics - RNA

外文摘要：Intestinal microbiota significantly affects the metabolism, digestion, and nutrient absorption of animals; however, these effects in teleost are not well defined. Taking Seriola dumerili as an example, 16S rRNA sequencing and LC-MS-based metabolomics were performed on different parts of the intestine. Significant variations in the microbiota structure existed in different intestine segments, Proteobacteria, Firmicutes, and Bacteroidetes were the three predominant phyla along the intestine. Photobacterium and Acinetobacter were likely to be in the core species in the intestines of S. dumerili. Potential probiotics and pathogens are mainly located in the anterior and posterior end of the intestines, respectively. A strong biofilm formation ability may be a crucial factor for the colonization and survival of numerous bacteria within the S. dumerili intestines. Different segments also present divergence in metabolism. The foregut is mainly related to lipid metabolism, while the hindgut is mainly related to the metabolism of amino acids and vitamins. Correlation analysis revealed the metabolic differences closely related to the biogeography distribution of gut microbiota. Isolated strains exhibited corresponding extracellular enzyme production in vitro, including proteinase, casease, lipase, lecithinase, and Urease. Thus, the intestinal microbiota may play an important role in the process of these nutrient metabolisms, further benefiting the rapid growth of the fish. ? 2024, The Authors. All rights reserved.