文献类型：期刊文献

英文题名：Newly discovered Asgard archaea Hermodarchaeota potentially degrade alkanes and aromatics via alkyl/benzyl-succinate synthase and benzoyl-CoA pathway

作者：Zhang, Jia-Wei[1,2];Dong, Hong-Po[1];Hou, Li-Jun[1];Liu, Yang[3];Ou, Ya-Fei[1];Zheng, Yan-Ling[4];Han, Ping[4];Liang, Xia[1];Yin, Guo-Yu[4];Wu, Dian-Ming[4];Liu, Min[4];Li, Meng[3]

机构：[1]East China Normal Univ, State Key Lab Estuarine & Coastal Res, Shanghai 200241, Peoples R China;[2]Guangdong Ocean Univ, Sch Ocean & Meteorol, Zhanjiang 524088, Peoples R China;[3]Shenzhen Univ, Inst Adv Study, Shenzhen Key Lab Marine Microbiome Engn, Shenzhen 518060, Peoples R China;[4]East China Normal Univ, Key Lab Geog Informat Sci, Minist Educ, Shanghai 200241, Peoples R China

年份：2021

卷号：15

期号：6

起止页码：1826

外文期刊名：ISME JOURNAL

收录：SCI-EXPANDED(收录号：WOS:000608003100003)、、Scopus(收录号：2-s2.0-85100048625)、WOS

基金：This study was supported by the National Natural Science Foundation of China (41971125, 41725002, 42030411, 91851105 and 31970105), the Guangdong Natural Science Foundation (2018A030313164), and the Innovation Study Project of East China Normal University. We thank Silvia E. Newell for editing this manuscript.

语种：英文

外文摘要：Asgard archaea are widely distributed in anaerobic environments. Previous studies revealed the potential capability of Asgard archaea to utilize various organic substrates including proteins, carbohydrates, fatty acids, amino acids and hydrocarbons, suggesting that Asgard archaea play an important role in sediment carbon cycling. Here, we describe a previously unrecognized archaeal phylum, Hermodarchaeota, affiliated with the Asgard superphylum. The genomes of these archaea were recovered from metagenomes generated from mangrove sediments, and were found to encode alkyl/benzyl-succinate synthases and their activating enzymes that are similar to those identified in alkane-degrading sulfate-reducing bacteria. Hermodarchaeota also encode enzymes potentially involved in alkyl-coenzyme A and benzoyl-coenzyme A oxidation, the Wood-Ljungdahl pathway and nitrate reduction. These results indicate that members of this phylum have the potential to strictly anaerobically degrade alkanes and aromatic compounds, coupling the reduction of nitrate. By screening Sequence Read Archive, additional genes encoding 16S rRNA and alkyl/benzyl-succinate synthases analogous to those in Hermodarchaeota were identified in metagenomic datasets from a wide range of marine and freshwater sediments. These findings suggest that Asgard archaea capable of degrading alkanes and aromatics via formation of alkyl/benzyl-substituted succinates are ubiquitous in sediments.