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Fabrication of a Quaternary Ammonium Chitosan/Pomelo Peel Extract Nanoparticle System for Tea Polyphenol Delivery: Characterization, Stability, Digestibility, and Release Properties  ( EI收录)   被引量:41

文献类型:期刊文献

英文题名:Fabrication of a Quaternary Ammonium Chitosan/Pomelo Peel Extract Nanoparticle System for Tea Polyphenol Delivery: Characterization, Stability, Digestibility, and Release Properties

作者:Ai, Chao[1]; He, Bo[1]; Luo, Xuanlin[1]; Wang, Ruo bing[1]; Kang, Jingling[2]; Li, Xinyi[2]; Xiao, Wenli[2]; Zhong, Zhaohong[2]; Chen, Lei[1]; Xie, Xi[2]; Liu, Huifan[2]

机构:[1] College of Food Science and Technology, Guangdong Ocean University, Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Guangdong Province Engineering Laboratory for Marine Biological Products, Guangdong Provincial Engineering Technology Research Center of Seafood, Guangdong Provincial Engineering Technology Research Center of Prefabricated Seafood Processing and Quality Control, Zhanjiang, 524088, China; [2] College of Light industry and Food, Zhongkai University of Agriculture and Engineering, Guangdong, Guangzhou, 510225, China

年份:2026

外文期刊名:SSRN

收录:EI(收录号:20260021971)

语种:英文

外文关键词:Chemical stability - Chitosan - Convergence of numerical methods - Encapsulation - Irradiation - Self assembly - Sludge digestion - System stability - Tea

外文摘要:The application of tea polyphenols is constrained by their inherent chemical instability. In this study, a nanoparticle delivery system for TP was fabricated via electrostatic self-assembly between a natural pomelo peel extract (PP) and quaternary ammonium chitosan (QAC). PP was characterized as a protein-pectin complex, containing 55.1% protein and 23.2% polysaccharides, of which 75.6% was galacturonic acid. PP formed stable complexes with QAC at pH ~4, achieving a TP encapsulation efficiency of 39.6%. The QAC-PP nanoparticle significantly improved TP stability under simulated gastrointestinal conditions, retaining 96.3% of TP after 1 h of gastric digestion and 59.5% after a subsequent 2 h of intestinal digestion. Furthermore, after 12 h of UV irradiation, 58.9% of encapsulated TP remained, substantially higher than the 43.0% retention observed for free TP. This work successfully valorizes pomelo peel waste into an effective nanocarrier, presenting a viable strategy to enhance the stability of TP. ? 2026, The Authors. All rights reserved.

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