文献类型：专著

英文题名：The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish

作者：Kalueff A.V.[1,2,3,4]

机构：[1]The International Zebrafish Neuroscience Research Consortium (ZNRC), ZENEREI Research Center, Slidell, LA, United States;[2]College of Food Science and Technology, Research Institute of Marine Drugs and Nutrition, Guangdong Ocean University, Zhanjiang, Guangdong, China;[3]Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russian Federation;[4]Institutes of Chemical Technology and Natural Sciences, Ural Federal University, Ekaterinburg, Russian Federation

出版社：Springer International Publishing

出版日期：0

纸书定价：0

isbn号：9783319337746; 9783319337739

语种：英文

外文摘要：Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) have become a very popular model organism in biomedical research. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans (~75% based on coding regions), it is not surprising that humans and fish are very similar physiologically (and behaviorally). Therefore, it should not come as a surprise that zebrafish can be an excellent model of human neuropsychiatric disorders. While some classical psychiatrists may not too easily be persuaded by this generalization, the current book "The rights and wrongs of zebrafish: principles of behavioral phenotyping and CNS disease modeling" explains, in a domain-by-domain manner, how exactly zebrafish models can be used to target a wide range of human brain disorders and aberrant phenotypes. The contributors to this book are leading international scholars whose work spearheads innovative zebrafish neuroscience research around the world. Written by top experts in the field, this book makes for a useful, balanced and up-to-date reading that outlines the use of zebrafish to study the pathological mechanisms underlying neuropsychiatric disorders. ? Springer International Publishing Switzerland 2017. All rights reserved.