文献类型：期刊文献

中文题名：杜仲多糖对三黄鸡免疫应答的佐剂作用

英文题名：Adjuvant Effects of Eucommia ulmoides Oliv.Polysaccharide on Immune Response of Sanhuang Chicken

作者：王凯[1];卢曦[1];刘艳芬[1];陈绍红[2];刘铀[2]

机构：[1]广东海洋大学农学院,广东湛江524088;[2]广东海洋大学生化中心,广东湛江524088

年份：2014

卷号：43

期号：1

起止页码：123

中文期刊名：河南农业科学

外文期刊名：Journal of Henan Agricultural Sciences

收录：CSTPCD、、北大核心2011、CSCD_E2013_2014、北大核心、CSCD

基金：广东省科技计划项目(2007A020200006-8)

语种：中文

中文关键词：三黄鸡;杜仲多糖;免疫佐剂;免疫应答

外文关键词：Sanhuang chicken; Eucommia ulmoides Oliv. polysaccharide; immune adjuvant; immune response

中文摘要：为研究杜仲多糖(EOP)对家禽免疫应答的影响,将120只1日龄三黄鸡随机分成A、B、C、D4组,分别接种含有0、2、5、8mg/mL EOP的新城疫和禽流感疫苗,检测相关免疫指标的变化。结果显示,添加8mg/mL EOP能显著提高三黄鸡新城疫和禽流感抗体水平、T淋巴细胞含量和白细胞吞噬指数(P<0.05),但对三黄鸡免疫器官指数、血清IgG含量影响不大(P>0.05)。可见,EOP对疫苗免疫具有佐剂作用,且EOP的添加量与其佐剂效果有一定的相关性。

外文摘要：The present study was aimed to investigate the effects of Eucommia ulmoides Oliv . Polysaccharide（EOP） on immune response of avain .120 1-day-old Sanhuang broilers were ran-domly divided into A ,B ,C and D four groups .The four groups were subsequently inoculated with Newcasttle disease and Avain influenza vaccines supplemented with 0 ,2 ,5 ,8 mg/mL doses of EOP respectively ,and the associated immune parameters were detected .The results indicated that the HI antibody tieters of Newcasttle disease and Avain influenza ,percentage of T lymphocytes and phagocytic index of white blood cells of group D were significantly elevated （P〈0 .05）owing to the EOP addition ,whereas the immune organ index and serum IgG content were not affected . It can be inferred that EOP had adjuvant effect on vaccine inoculation and there was some dose-effect relationship between them .