文献类型：期刊文献

英文题名：Heat stress exposure changed liver lipid metabolism and abdominal fat deposition in broilers

作者：Lan, Ruixia[1];Wang, Yuchen[1];Wei, Linlin[1];Wu, Fan[1];Yin, Fuquan[1]

机构：[1]Guangdong Ocean Univ, Coll Coastal Agr Sci, Dept Anim Sci, Zhanjiang, Peoples R China

年份：2022

卷号：21

期号：1

起止页码：1326

外文期刊名：ITALIAN JOURNAL OF ANIMAL SCIENCE

收录：SCI-EXPANDED(收录号：WOS:000842634000001)、、Scopus(收录号：2-s2.0-85135988669)、WOS

基金：This work was supported by the program for scientific research start-up funds of Guangdong Ocean University (101402/R18005).

语种：英文

外文关键词：Broiler; heat stress; liver; lipid metabolism; abdominal adipose deposition

外文摘要：To evaluate the effects of heat stress on lipid metabolism in the liver and abdominal adipose deposition in broilers, totally, 120 female 21-day old broilers were selected and randomly allocated to 2 groups with 6 replication and 10 broilers per each replication. Broilers in the control group (CON) were reared at 24 degrees C, and broilers in the heat stress group (HS) were reared at 34 degrees C. Heat stress exposure increased (P < 0.05) rectal temperature, relative weight of abdominal adipose and liver, serum triacylglycerol (TG) and total cholesterol (TC) level, liver TG, TC, and very low-density lipoprotein (VLDL) content. Hepatic mRNA expression level of fatty acid synthase (FAS), acetyl-coenzyme A carboxylase (ACC), and abdominal adipose mRNA expression level of ACC and CCAAT/enhancer-binding protein-alpha (C/EBP alpha) were up-regulated (P < 0.05) when compared with the CON group. Heat stress exposure increased serum and hepatic TC and TG content, up-regulated the mRNA expression of FAS and ACC in liver, and promoted preadipocytes differentiation by increasing C/EBP alpha mRNA expression in abdominal adipose. Therefore, heat stress exposure increased abdominal adipose deposition, which related to increase in hepatic de novo lipogenesis, and promoted preadipocytes differentiation in abdominal adipose.