文献类型：期刊文献

英文题名：Fabrication and Characterization of Marine Polysaccharides Hemostatic Dressing

作者：Zhong, Qing-Kun[1,2]; Hu, Zhang[1]; Zhang, Dong-Ying[1]; Li, Si-Dong[1]

机构：[1] Faculty of Chemistry and Environmental Science, Guangdong Ocean University, Zhanjiang, 524088, China; [2] School of Ocean and Meteorology, Guangdong Ocean University, Zhanjiang, 524088, China

年份：2018

卷号：423

期号：1

外文期刊名：IOP Conference Series: Materials Science and Engineering

收录：EI(收录号：20184906171133)

语种：英文

外文关键词：Calcium chloride - Fabrication - Scanning electron microscopy - Sodium alginate - Chitosan - Morphology - Swelling

外文摘要：Marine polysaccharides composite hemostatic dressing was fabricated with calcium chloride as the crosslinking agent and carboxymethyl chitosan/sodium alginate as raw materials. On the basis of the pre-experiment, the fabrication process of marine polysaccharides hemostatic dressing was optimized by response surface methodology. The dressing prepared under the optimum conditions was characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR), and then its hemostatic performance was evaluated. The results showed that the optimum conditions for the preparation of hemostatic dressing were as follows: concentration of CMCS is 0.5%, mass ratio of CMCS and SA is 1: 2.5, concentration of CaCl2 is 1.5%. And the swelling ratio of the dressing reached 8020%. FTIR showed that the crosslinking between carboxymethyl chitosan and sodium alginate was successful. Morphology observation found that the appearance was smooth, the pores were large and uniform. Furthermore, the dressing had good coagulation performance. ? 2018 Institute of Physics Publishing. All rights reserved.