文献类型：期刊文献

英文题名：Efficient synthesis of 2,4-dioxo-hexahydro-1,3,5-triazine O-acetyl-glycosyl glucosides and their antiviral activity

作者：Chen, H.[1];Huang, S-Q[1];Xie, J. -Y.[1]

机构：[1]Guangdong Ocean Univ, Dept Appl Chem, Zhanjiang 524088, Peoples R China

年份：2009

卷号：45

期号：8

起止页码：976

外文期刊名：CHEMISTRY OF HETEROCYCLIC COMPOUNDS

收录：SCI-EXPANDED(收录号：WOS:000272158000011)、、EI(收录号：20242616432155)、Scopus(收录号：2-s2.0-72249105776)、WOS、CCR-EXPANDED(收录号：WOS:000272158000011)

基金：We thank the Department of Education of Guangdong Province Natural Science Foundation of China for financial support. Helpful discussion with Professor Xiaoling Huang is also acknowledged.

语种：英文

外文关键词：O-acetylglycosyl; O-acetylglycosyl glucoside; 2,4-dioxohexahydro-1,3,5-triazine; DMAP/Et3N; tobacco mosaic virus

外文摘要：Four 2,4-dioxohexahydro-1,3,5-triazine O-acetylglycosyl glucosides were synthesized through glucoside formation reactions at room temperature using 4-dimethylaminopyridine as a catalyst and triethylamine as a deacidification reagent. Their structure was confirmed by IR, H-1 NMR spectra, MS, and elemental analysis. The synthesized compounds are all of beta-configuration. The results show that DMAP is an effective catalyst; the yields can reach 83.7%. The above glucosides showed an improved antiviral activity against tobacco mosaic virus.