文献类型：期刊文献

英文题名：Metabolic dysfunctions in pearl oysters following recurrent marine heatwaves

作者：He, Guixiang[1];Liu, Xiaolong[1];Xu, Yang[1];Liu, Yong[2];Masanja, Fortunatus[1];Deng, Yuewen[1];Zhao, Liqiang[1,3,4]

机构：[1]Guangdong Ocean Univ, Fisheries Coll, Zhanjiang, Peoples R China;[2]Guangdong Ocean Univ, Pearl Oyster Res Inst, Zhanjiang, Peoples R China;[3]Guangdong Ocean Univ, Guangdong Prov Sci & Technol Innovat Ctr Marine In, Zhanjiang, Peoples R China;[4]Guangdong Ocean Univ, Guangdong Prov Key Lab Aquat Anim Dis Control & Hl, Zhanjiang, Peoples R China

年份：2024

卷号：200

外文期刊名：MARINE ENVIRONMENTAL RESEARCH

收录：SCI-EXPANDED(收录号：WOS:001273234200001)、、EI(收录号：20242916708165)、Scopus(收录号：2-s2.0-85198351255)、WOS

基金：The present study has been made possible by grants from the National Science Foundation of China (42076121, M-0163, 42211530423) , the Department of Education of Guangdong Province (2020KTSCX050 and 2022ZDZX4012) , the Postgraduate Education Innovation Project of Guangdong Ocean University (202273) , the China Scholarship Council (NO. 2023-21) , the Guangdong Zhujiang Talents Program (2021QN02H665) , and the program for Scientific Research Start-up Funds of Guangdong Ocean University.

语种：英文

外文关键词：Climate change; Marine heatwaves; Pinctada maxima; Metabolism

外文摘要：Marine heatwaves (MHWs) have become more frequent, intense and extreme in oceanic systems in the past decade, resulting in mass mortality events of marine invertebrates and devastating coastal marine ecosystems. While metabolic homeostasis is a fundamental requirement in stress tolerance, little is known about its role under intensifying MHWs conditions. Here, we investigated impacts of MHWs on the metabolism in pearl oysters (Pinctada maxima) - an ecologically and economically significant bivalve species in tropical ecosystems. Activities of digestive enzymes (gastric proteases, lipases, and amylases) did not significantly respond to various scenario of recurrent MHWs varying from 24 degrees C to 28 degrees C (moderate) and 32 degrees C (severe). The metabolomics analysis revealed nine and five key metabolism pathways under both MHWs scenarios. Specifically, pathways associated with energy metabolism were impaired by moderate MHWs, manifesting in downregulation of differential metabolite (The nicotinic acid and N-acetyl-glutamic acid). The content of CDP-ethanolamine was significantly decrease, and the perturbations of oxidative stress caused by the decreased of content of D-glutamine. Metabolites related to a suite of body functions (e.g., the lipid metabolism, biomineralization, and antioxidant defenses) showed significantly negative responses by severe MHWs. These findings reveal the metabolic impairments of marine bivalves when subjected to MHWs varying in intensity and frequency, implying cascading consequences which deserve further investigation.