文献类型：期刊文献

英文题名：Probiotics and paraprobiotics in aquaculture: a sustainable strategy for enhancing fish growth, health and disease prevention-a review

作者：Fachri, Muhammad[1,2,3,4];Amoah, Kwaku[1,5,6,7,8];Huang, Yu[1,5,6,7,8];Cai, Jia[1,5,6,7,8];Alfatat, Alma[1];Ndandala, Charles Brighton[1,2,3,4];Shija, Vicent Michael[1,5,6];Jin, Xiao[1,5,6,7,8];Bissih, Fred[1];Chen, Huapu[1,2,3,4]

机构：[1]Guangdong Ocean Univ, Coll Fisheries, Zhanjiang, Peoples R China;[2]Agro Tech Extens Ctr Guangdong Prov, Guangzhou, Peoples R China;[3]Guangdong Res Ctr Reprod Control & Breeding Techno, Zhanjiang, Peoples R China;[4]Guangdong Prov Key Lab Pathogen Biol & Epidemiol A, Zhanjiang, Peoples R China;[5]Guangdong Ocean Univ, Guangdong Prov Key Lab Aquat Anim Dis Control & Hl, Zhanjiang, Peoples R China;[6]Guangdong Higher Educ Inst, Key Lab Control Dis Aquat Anim, Zhanjiang, Peoples R China;[7]Guangdong Prov Engn Res Ctr Aquat Anim Hlth Assess, Shenzhen, Peoples R China;[8]Guangdong Ocean Univ, Shenzhen Inst, Shenzhen, Peoples R China

年份：2024

卷号：11

外文期刊名：FRONTIERS IN MARINE SCIENCE

收录：SCI-EXPANDED(收录号：WOS:001381881200001)、、Scopus(收录号：2-s2.0-85212777574)、WOS

基金：The author(s) declare financial support was received for the research, authorship, and/or publication of this article. The research leading to these results was financially supported by the National Natural Science Foundation of China (32273131), the Program for Scientific Research Start-up Funds of Guangdong Ocean University (060302022310), the Key Research and Development Program of Guangdong (2021B02020200020), the Science and Technology Plan of Guangdong Province (2023B0202010016), the Youth Science and Technology Innovation Talent of Guangdong TeZhi plan talent (2023TQ07A888), the Research on breeding technology of candidate species for Guangdong modern marine ranching (2024-MRB-00-001) and the Science and Technology Plan of Zhanjiang City (2024E03007).

语种：英文

外文关键词：probiotics; paraprobiotics; bacteriocins; disease resistance; probiogenomics; sustainable aquaculture; gut microbiota modulation

外文摘要：This review delves into the increasing interest in probiotics and paraprobiotics as a viable alternative to antibiotics in aquaculture, highlighting their potential to enhance fish health and prevent diseases. As the aquaculture industry continues its global expansion, addressing the challenges associated with disease outbreaks in high-density fish populations becomes imperative. The review underscores the promising role of probiotics and paraprobiotics as a sustainable strategy to mitigate these challenges. The diverse positive impacts of various probiotic strains such as Arthrobacter, Bacillus, Lactobacillus, Bifidobacterium, Clostridium, and others emphasize their roles in enhancing growth, resistance to diseases (including bacterial, viral, and parasitic infections), stress reduction, water quality management, and environmental sustainability. Challenges such as stability, host specificity, and regulatory considerations must be addressed to optimize the use of probiotics in aquaculture. Additionally, paraprobiotics, or non-viable microbial cells, present a safer alternative to the criticized antibiotics and even live probiotics in environments where microbial viability poses a risk. These inactivated cells retain the ability to modulate the immune system and improve gut health, offering a promising complementary approach to fish disease prevention. The review advocates for a systematic approach combining research, innovation, and collaboration to effectively integrate probiotics and paraprobiotics into fish farming practices. Furthermore, the mechanisms by which probiotics and paraprobiotics modulate gut microbiota, produce antimicrobial compounds, and strengthen fish's immune system have been elucidated. Moreover, the practical applications of probiotics in fish farming, including optimal administration methods and the challenges and limitations faced by the industry, have been discussed. Emphasis on the importance of continued research to explore new probiotic and paraprobiotic strains and develop innovative delivery systems to ensure the sustainability of aquaculture has been discussed. By enhancing fish health, reducing the need for antibiotics, and improving water quality, probiotics, and paraprobiotics contribute to more sustainable and environmentally responsible aquaculture operations.