文献类型：期刊文献

英文题名：Cross-resistance and adaptive persistence of Listeria monocytogenes under multiple food-grade sanitizer stresses: molecular mechanisms and control implications

作者：Cheng, Yue[1,2,3,4,5];Tang, Jiafei[1,2,3,4,5];Wei, Shuai[1,2,3,4,5,6]

机构：[1]Guangdong Ocean Univ, Coll Food Sci & Technol, 1 Haida Rd, Zhanjiang 524088, Peoples R China;[2]Guangdong Prov Key Lab Aquat Prod Proc & Safety, Zhanjiang, Peoples R China;[3]Guangdong Prov Engn Lab Marine Biol Prod, Zhanjiang, Peoples R China;[4]Guangdong Prov Engn Technol Res Ctr Seafood, Zhanjiang, Peoples R China;[5]Guangdong Prov Engn Technol Res Ctr Prefabricated, Zhanjiang, Peoples R China;[6]Dalian Polytech Univ, Collaborat Innovat Ctr Seafood Deep Proc, Dalian, Peoples R China

年份：2026

卷号：10

外文期刊名：FOOD QUALITY AND SAFETY

收录：SCI-EXPANDED(收录号：WOS:001691826700001)、、Scopus(收录号：2-s2.0-105030282363)、WOS

基金：This study was supported by the Key Project of the Department of Education of Guangdong Province (No. 2022ZDZX4014) and the Scientific Research Start-Up Funds of Guangdong Ocean University (No. R20048), China.

语种：英文

外文关键词：Listeria monocytogenes; sanitizer tolerance; cross-resistance; stress response; omics technologies; predictive modeling

外文摘要：Listeria monocytogenes can persist in food-processing environments despite repeated exposure to various food-grade sanitizers. This review summarizes and compares current knowledge on the molecular basis of L. monocytogenes tolerance and persistence to quaternary ammonium-, chlorine-, and peroxide-based agents, as well as emerging sanitization agents or stresses. Efflux-mediated detoxification, membrane modification, oxidative stress response, and biofilm formation are discussed as key adaptive mechanisms contributing to cross-resistance. The convergent and divergent features of these mechanisms among different sanitizer classes are highlighted, providing an integrative perspective on tolerance development. The influence of sublethal exposure, organic load, and multispecies biofilms on long-term persistence is also examined. These insights contribute to the development of predictive hygiene control and evidence-based sanitation strategies for enhanced food safety management.