文献类型：期刊文献

英文题名：Electrospinning of chitosan/polyvinyl alcohol Pickering emulsion with tea tree essential oil loaded for anti-infection wound dressings

作者：Jiang, Tiangao[1];Wang, Di[1];Zhang, Xueqin[2];Yang, Qian[1];Huang, Qinfang[1];Ju, Xianghong[1,3];Li, Lefan[1];Kang, Xinhuang[4,5];Li, Chengpeng[1,4,5]

机构：[1]Guangdong Ocean Univ, Sch Chem & Environm Sci, Zhanjiang 524088, Peoples R China;[2]Huaqiao Univ, Coll Chem Engn, Xiamen 361021, Peoples R China;[3]Coll Coastal Agr Sci, Zhanjiang 524088, Peoples R China;[4]Zhanjiang Key Lab Comprehens Utilizat Chem Res Mar, Zhanjiang 524088, Peoples R China;[5]Zhanjiang Key Lab Marine Biomat Res, Zhanjiang 524088, Peoples R China

年份：2024

卷号：311

外文期刊名：MATERIALS CHEMISTRY AND PHYSICS

收录：SCI-EXPANDED(收录号：WOS:001098624800001)、、EI(收录号：20234214904483)、Scopus(收录号：2-s2.0-85173840108)、WOS

基金：This work was financially supported by Project of Zhanjiang Science & Technology Plan (2021A05041) , The Foreign Cooperation Project of Fujian Province (No.2022I0016) , Entrepreneurship Training Team Program of Guangdong Ocean University (No. 521201004029) , Zhanjiang Key Laboratory of Comprehensive Utilization of Chemical Research for Marine Resources (No. A14457) , Zhanjiang Key Laboratory of Marine Bio-materials Research (No. A15445) .

语种：英文

外文关键词：Electrospinning; Tea tree essential oil; Pickering emulsion; Antibacterial activity

外文摘要：As a natural antibacterial agent, Tea tree oil (TTO) possesses low aqueous solubility. To load TTO in hydrophilic hydroxyethyl chitosan/polyvinyl alcohol nanofiber matrix, Pickering emulsion electrospinning strategy using ZnO/Ag nano composite (ZA) as stabilizer was proposed for anti-infection dressing development. Under the stabilizing assistance of ZA particles in the size range of 53 and 59 nm, Pickering emulsions with homogenously distributed TTO droplets show good stability, which can be further elctrospun into continuously bead-on-string nanofibers under optimized processing conditions. In spite of the volatilization of TTO during electrospinning, the nanofibers possess good and long-term antibacterial activity against both gram-positive and gram-negative bacteria. In vitro experiments indicated that the nanofibers possess superior hemocompatibility and cyto-compatibility. Particularly, it can promote the cell proliferation and migration when its concentration is 800 mu g/ mL or less. In conclusions, Pickering emulsion electrospinning is a feasible strategy for the fabrication of nanofibers loaded with hydrophobic TTO and the as-obtained nanofibers can be potentially applied in infected wounds.