文献类型：期刊文献

英文题名：Green Synthesis of Selenium Nanoparticles Mediated by Nilgirianthus ciliates Leaf Extracts for Antimicrobial Activity on Foodborne Pathogenic Microbes and Pesticidal Activity Against Aedes aegypti with Molecular Docking

作者：Meenambigai, Krishnan[1];Kokila, Ranganathan[1];Chandhirasekar, Kandasamy[1];Thendralmanikandan, Ayyavu[1];Kaliannan, Durairaj[2];Ibrahim, Kalibulla Syed[3];Kumar, Shobana[4];Liu, Wenchao[5];Balasubramanian, Balamuralikrishnan[6];Nareshkumar, Arjunan[1]

机构：[1]Periyar Univ, Sch Life Sci, Dept Zool, Salem 636011, India;[2]Periyar Univ, Sch Life Sci, Dept Environm Sci, Salem 636011, India;[3]PSG Coll Arts Sr Sci, PG & Res Dept Bot, Coimbatore 641014, Tamil Nadu, India;[4]Sri GVG Visalakshi Coll Women, Dept Zool, Udumalpet, Tamil Nadu, India;[5]Guangdong Ocean Univ, Coll Coastal Agr Sci, Dept Anim Sci, Zhanjiang 524088, Peoples R China;[6]Sejong Univ, Coll Life Sci, Dept Food Sci & Biotechnol, Seoul, South Korea

年份：2022

卷号：200

期号：6

起止页码：2948

外文期刊名：BIOLOGICAL TRACE ELEMENT RESEARCH

收录：SCI-EXPANDED(收录号：WOS:000687927800001)、、WOS

基金：Authors are thankful to the University Grants Commission (UGC), New Delhi, India, for the award of Rajiv Gandhi National Fellowship with financial support (Ref No: F1-17.1/2015-16/RGNF2015-17 -SC-TAM-10313) to carry out this research work.

语种：英文

外文关键词：Nilgirianthus ciliates; Selenium nanoparticles; Aedes aegypti; Foodborne pathogens; In silico docking

外文摘要：The present study deals with the synthesis of selenium nanoparticles (SeNPs) using Nilgirianthus ciliatus leaf extracts, characterized by UV-Vis spectrophotometer, XRD, FTIR, FE-SEM, HR-TEM, DLS, and zeta potential analysis. The antimicrobial activity against Staphylococcus aureus (MTCC96), Escherichia coli (MTCC443), and Salmonella typhi (MTCC98) showed the remarkable inhibitory effect at 25 mu l/mL concentration level. Furthermore, the characterized SeNPs showed a great insecticidal activity against Aedes aegypti in the early larval stages with the median Lethal Concentration (LC50) of 0.92 mg/L. Histopathological observations of the SeNPs treated midgut and caeca regions of Ae. aegypti 4th instar larvae showed damaged epithelial layer and fragmented peritrophic membrane. In order to provide a mechanistic approach for further studies, molecular docking studies using Auto Dock Vina were performed with compounds of N. ciliatus within the active site of AeSCP2. Overall, the N. ciliates leaf-mediated biogenic SeNPs was promisingly evidenced to have potential larvicidal and food pathogenic bactericidal activity in an eco-friendly approach.