文献类型：期刊文献

英文题名：Novel method for the synthesis of bioactive benzimidazolyl-phenoxyacetic acid O-acetylglucosyl saccharide esters

作者：Chen, Hong[1]; Chen, Yunhua[2]; Ou, Chunyan[1]; Huang, Siqing[1]

机构：[1] Department of Applied Chemistry, Guangdong Ocean University, Zhanjiang 524088, China; [2] Department of Chemistry, Nanchang University, Nanchang 330047, China

年份：2006

卷号：11

期号：2

起止页码：419

外文期刊名：Wuhan University Journal of Natural Sciences

收录：EI(收录号：2006209883072)、Scopus(收录号：2-s2.0-33646511967)

语种：英文

外文关键词：Antiplantviral activity; Benzimidazolyl-phenoxyacetic acid; DMAP/Et₃N; O-acetylglucosyl saccharide ester

外文摘要：A novel-method of synthesis of nitro or trifluoromethyl substituted benzimidazolyl-phenoxyacetic acid O-acetylglucosyl saccharide esters by the reaction of O-acetylglucosyl bromide with substituted benzimidazolyl-phenoxyacetic acid at room temperature was developed. 4-dimethylaminopyridine (DMAP) was used as catalyst, triethylamine (Et3N) was used as deacid reagent, three saccharide esters were synthesized in the system of DMAP/Et3N. The catalytic mechanism of DMAP/Et3N was discussed. The results show that DMAP is an effective catalyst, the yields can reach 50%. The test indicates that the title compounds show better antiplantviral activity.