文献类型：期刊文献

英文题名：A sensitive nonenzymatic glucose sensor in alkaline media with a copper nanocluster/multiwall carbon nano tube-modified glassy carbon electrode

作者：Kang X.[1,2];Mai Z.[1];Zou X.[1];Cai P.[1];Mo J.[1]

机构：[1]Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Peoples R China;[2]Guangdong Ocean Univ, Coll Sci, Zhanjiang 524088, Peoples R China

年份：2007

卷号：363

期号：1

起止页码：143

外文期刊名：ANALYTICAL BIOCHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:000245155500016)、、EI(收录号：20201908631302)、Scopus(收录号：2-s2.0-33847343341)、WOS

基金：The authors acknowledge financial support from the National Natural Science Foundation of China (20475068 and 20575082), the Natural Science Foundation of Guangdong Province (031577), and the Scientific Technology Project of Guangdong Province (2005B30101003).

语种：英文

外文关键词：copper nanoclusters; carbon nanotubes; glucose; nonenzymatic sensor; electrodeposition

外文摘要：Copper (Cu) nanoclusters were electrochemically deposited on the film of a Nafion-solubilized muldwall carbon nanotube (CNTs)modified glassy carbon electrode (CNTs-GCE), which fabricated a Cu-CNTs composite sensor (Cu-CNTs-GCE) to detect glucose with nonenzyme. Transmission electron microscopy (TEM) and X-ray diffraction (XRD) were used for the characterization of the distribution of the Cu nanoclusters on the CNTs matrix. The composite of the Cu-CNTs was investigated by the electrochemical characterization of cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The preliminary study shows that the nonenzymatic sensor has synergistic electrocatalytic activity to the oxidation of glucose in alkaline media. A well applicable sensor was constructed to use for the analysis of the glucose in real blood serum samples due to the large number of electrons taking part in the oxidation process, the high apparent kinetic rate constant, and the stable operation of the electrode. The linear range for the detection of the glucose is 7.0 x 10(-7) to 3.5 x 10(-3) M with a high sensitivity of 17.76 mu A mM(-1), a low detection limit of 2.1 x 10(-7) M, and a fast response time of within 5 s. Experiment results also showed that the sensor has good reproducibility and long-term stability and is interference free. (c) 2007 Elsevier Inc. All rights reserved.