文献类型：期刊文献

中文题名：负载橙皮苷的玉米醇溶蛋白基纳米粒子的制备、表征及稳定性研究

英文题名：Preparation,Characterization and Stability of Zein Based Nanoparticles Loaded with Hesperidin

作者：雍凡星[1];康钰钊[1];陈泽恒[1];邓家欣[1];钟赛意[1,2];李瑞[1,2]

机构：[1]广东海洋大学食品科技学院,广东省水产品加工与安全重点实验室,广东省海洋生物制品工程实验室,广东省海洋食品工程技术研究中心,亚热带果蔬加工创新中心,广东湛江524088;[2]广东海洋大学深圳研究院,广东深圳518108

年份：2025

卷号：46

期号：20

起止页码：135

中文期刊名：食品工业科技

外文期刊名：Science and Technology of Food Industry

收录：北大核心2023、、EI(收录号：20254219327866)、北大核心

基金：广东省高等学校科技创新团队项目(2021KCXTD021);广东省高校生物医学与健康重点领域专项资金(2023ZDZX2025);广东海洋大学科研启动费资助项目(R20078)。

语种：中文

中文关键词：纳米粒子;橙皮苷;玉米醇溶蛋白;岩藻多糖;酪蛋白酸钠

外文关键词：nanoparticles;hesperidin;zein;fucoidan;sodium caseinate

中文摘要：为制备纳米粒子并用于橙皮苷(Hesperidin,HP)的包埋,本研究采用pH驱动法制备玉米醇溶蛋白(Zein,ZE)-酪蛋白酸钠(Sodium Caseinate,SC)-岩藻多糖(Fucoidan,FD)三元复合纳米粒子,并优化其制备条件;采用傅里叶变换红外光谱(Fourier Transform Infrared Spectroscopy,FTIR)探讨了ZE、SC、FD和HP之间的相互作用,利用扫描电子显微镜(Scanning Electron Microscope,SEM)观察纳米粒子的微观形貌,并研究了该纳米粒子的pH稳定性和离子稳定性。结果表明,ZE-SC-FD最佳的质量比为1:1:1;负载HP后的HP-ZE-SCFD纳米粒子平均粒径为101.8±0.7 nm,zeta电位为?36.1±1.0 mV,HP的包埋率为84.35%;FTIR结果表明,ZE、SC、FD和HP之间主要作用力包括氢键、静电和疏水相互作用;SEM结果显示,HP-ZE-SC-FD纳米粒子微观形态呈球形或椭球形颗粒;HP-ZE-SC-FD纳米粒子在pH2.0~8.0和NaCl浓度0~3.0 mol/L范围内具有良好的稳定性。本研究表明,ZE-SC-FD纳米粒子是一种包埋和保护HP的良好载体,可为含HP的功能性食品或保健品的研究及开发提供理论依据。

外文摘要：In order to prepare nanoparticles for inclusion of hesperidin(HP),the pH-driven method was used in this study to prepare zein(ZE)-sodium caseinate(SC)-fucoidan(FD)ternary composite nanoparticle,and its preparation conditions were optimized.The interactions between ZE,SC,FD and HP were investigated by Fourier transform infrared spectroscopy(FTIR),and the micromorphology of the nanoparticles was observed by scanning electron microscopy(SEM).The pH stability and ion stability of the nanoparticles were also studied.The results showed that the optimum mass ratio of Zein-SC-FD was 1:1:1.The average particle size of HP-ZE-SC-FD nanoparticles loaded with HP was 101.8±0.7 nm,its zeta potential was?36.1±1.0 mV,and the encapsulation efficiency of HP was 84.35%.The results of FTIR showed that the main forces between ZE,SC,FD and HP included hydrogen bonding,electrostatic and hydrophobic interactions.The SEM results showed that the microstructure of HP-ZE-SC-FD nanoparticles was spherical or ellipsoidal.HP-ZE-SC-FD nanoparticles showed good stability in the range of pH2.0~8.0 and NaCl concentration 0~3.0 mol/L.This study shows that ZE-SC-FD nanoparticles are a good carrier for encapsulating and protecting HP,which can provide a theoretical basis for the research and development of functional foods or health products containing HP.