文献类型：期刊文献

英文题名：Impacts of Aegle marmelos fruit extract as a medicinal herb on growth performance, antioxidant and immune responses, digestive enzymes, and disease resistance against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus)

作者：Wangkahart, Eakapol[1];Wachiraamonloed, Suriyet[1];Lee, Po-Tsang[2];Subramani, Parasuraman Aiya;Qi, Zhitao[3];Wang, Bei[4]

机构：[1]Mahasarakham Univ, Appl Anim & Aquat Sci Res Unit, Lab Fish Immunol & Nutrigen, Fac Technol,Div Fisheries, Kantarawichai 44150, Mahasarakham, Thailand;[2]Natl Taiwan Ocean Univ, Dept Aquaculture, Keelung 20224, Taiwan;[3]Yancheng Inst Technol, Jiangsu Key Lab Biochem & Biotechnol Marine Wetla, Yancheng 224051, Jiangsu, Peoples R China;[4]Guangdong Ocean Univ, Coll Fishery, Key Lab Control Dis Aquat Anim Guangdong Higher E, Guangdong Prov Key Lab Pathogen Biol & Epidemiol, Zhanjiang, Peoples R China

年份：2022

卷号：120

起止页码：402

外文期刊名：FISH & SHELLFISH IMMUNOLOGY

收录：SCI-EXPANDED(收录号：WOS:000734877200002)、、WOS

基金：This research project was financially supported by Mahasarakham University.

语种：英文

外文关键词：Blood cholesterol; Bacterial challenge; Active ingredients; Herbal medicines; Aquafeed industry; Immunomodulator; Sustainable aquaculture; Dietary supplementation

外文摘要：An experiment was conducted to investigate the effects of Aegle marmelos fruit (AMF) extract on the growth performance, biochemical parameters, immune response, antioxidative capacity, and digestive enzyme activity of Nile tilapia (Oreochromis niloticus). Fish were fed a diet supplemented with AMF at concentrations of 0 (AMF0; control), 5 (AMF5), 10 (AMF10), 15 (AMF15), or 20 (AMF20) g/kg for 8 weeks. The results show that the final body weight, weight gain, specific growth rate, average daily gain, and feed conversion ratio were significantly higher in fish fed AMF15 and AMF20 compared to those fed the control diet (P < 0.05). Moreover, significant increases in antioxidant enzyme activities and non-specific immune responses were observed in groups fed AMF15 and AMF20. Interestingly, the level of cholesterol decreased with increasing AMF concentrations in the diet. As dietary AMF levels increased, digestive enzyme activities significantly improved. After the feeding trial, fish were injected intraperitoneally with Streptococcus agalactiae, and the 14-day cumulative mortality was calculated. A high survival rate after challenge with S. agalactiae was observed in all groups that received AMFsupplemented feed. Therefore, the present study suggests that supplementing the diet of Nile tilapia with AMF at a concentration of 20 g/kg could encourage their growth, improve their immunity and antioxidant status, and provide strong protection against S. agalactiae.