文献类型：期刊文献

中文题名：Oyster Protein Hydrolysate Alleviates Cadmium Toxicity by Restoring Cadmium-Induced Intestinal Damage and Gut Microbiota Dysbiosis in Mice via Its Abundance of Methionine,Tyrosine,and Glutamine

作者：WANG Jing Wen[1];FANG Zhi Jia[1];LI Yong Bin[1];HUANG Lin Ru[1];SUN Li Jun[1];LIU Ying[1];WANG Ya Ling[1];LIAO Jian Meng[2]

机构：[1]College of Food Science and Technology,Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety,Guangdong Provincial Engineering Technology Research Center of Marine Food,Key Laboratory of Advanced Processing of Aquatic Products of Guangdong Higher Education Institution,Guangdong Ocean University,Zhanjiang 524088,Guangdong,China;[2]Institute for Food and Drug Control,Zhanjiang 524088,Guangdong,China

年份：2022

卷号：35

期号：7

起止页码：669

中文期刊名：Biomedical and Environmental Sciences

外文期刊名：生物医学与环境科学（英文版）

收录：CSCD2021_2022、Scopus、CSCD、PubMed

基金：This work was supported by the National Natural Science Foundation of China [No. 32172215 and 31701706]; the Program for Scientific Research Start-up Funds of the Guangdong Ocean University [No. R17102]; Characteristic Innovation Project of Guangdong Province [No. 2018KTSCX089]; and Guangdong Basic and Applied Basic Research Foundation [No. 2019A1515010809, 2021A1515012443].

语种：英文

中文关键词：prevention;alterations;cadmium;

中文摘要：As a typical heavy metal contaminant in food,cadmium(Cd)easily enters the human food chain via crop production,and therefore,threatens human health[1].Intestinal absorption is the principal route for Cd entry into the body,and therefore,intestinal tissue become the primary target for Cd toxicity[2].Previous studies showed that acute Cd exposure damaged intestinal tight junctions,resulting in gut barrier destruction and alterations in gut microbiota[3].Thus,the effective prevention of Cd-induced intestinal damage has become a major research challenge.