文献类型：期刊文献

中文题名：动物替抗天然产物的研究及应用进展

英文题名：Research and Application Progress of Natural Alternatives to Antibiotics for Animal

作者：巨向红[1,2]

机构：[1]广东海洋大学动物医学系,广东湛江524000;[2]广东海洋大学深圳研究院,广东深圳518108

年份：2023

卷号：48

期号：3

起止页码：8

中文期刊名：广东畜牧兽医科技

外文期刊名：Guangdong Journal of Animal and Veterinary Science

基金：国家自然基金(32273077)。

语种：中文

中文关键词：替抗;减抗;天然产物;畜禽健康

外文关键词：Antibiotics;Replacement;Reduce;Natural product;Animal health

中文摘要：全球每年的抗生素消耗量巨大,致使细菌耐药性和药物残留问题日益突出,“超级细菌”的发生频率及概率陡增,对人类及畜禽健康构成重大威胁。尽管欧美等发达国家及我国都相继出台了系列“禁抗限抗”政策,但非洲及东南亚部分国家的抗生素使用仍存在监管不足、过量使用等乱象,细菌耐药性问题的长期威胁依然存在。因此,寻找有效减抗替抗天然产物以较少抗生素使用成为行业的关注焦点。中草药、益生菌、抗菌肽、酸化剂、酶制剂及兽用海洋药物等表现出优良的抗菌、抑炎、免疫力增强及促生长功能,绿色无抗养殖技术被不断突破并成为趋势。该文综述了我国抗生素使用现状以及替抗天然产物的功能作用、存在问题及可能的解决途径。

外文摘要：The huge consumption of antibiotics by human and animal industry in the world has resulted in severe problems of bacterial resistance and drug residue,the rate and probability of the occurrence of“superbacteria”increased significantly,presenting threat to human and animal health.Although developed countries such as the Europe union and the United States of American,and our country,have successively issued a series of policies to decrease the consumption of antibiotics,its use in some developing countries such as Africa and Southeast Asia,still is insufficiently supervised and excessive used,and the long?term threat of bacterial resistance still exists.Therefore,the search of effective natural products to reduce the use of antibiotics is vital.Now,Chinese herbal medicine,probiotics,antimicrobial peptides,acidifiers,enzyme,and animal used marine drugs,all showed excellent antibacterial,anti?inflammatory,immunity enhancement,and growth?promoting functions.A green,antibiotics?free breeding technology in animal industry is of tendency in future.This paper reviewed the current situation of antibiotics used in China,as well as the antibiotics replacement products,focused on their function and acting mechanism,problems occurred in usage,and possible solutions for dealing with these problems.