文献类型：期刊文献

英文题名：Identification of EGFR in pearl oyster (Pinctada fucata martensii) and correlation analysis of its expression and growth traits

作者：Wang, Qingheng[1,2];Hao, Ruijuan[1];Zhao, Xiaoxia[3];Huang, Ronglian[1,2];Zheng, Zhe[1,2];Deng, Yuewen[1,2];Chen, Weiyao[2];Du, Xiaodong[1,2]

机构：[1]Guangdong Ocean Univ, Fisheries Coll, Zhanjiang, Peoples R China;[2]Res Ctr Guangdong Prov, Pearl Breeding & Proc Engn Technol, Zhanjiang, Peoples R China;[3]Environm Protect Agcy Zhanjiang, Environm Protect Monitoring Stn, Zhanjiang, Peoples R China

年份：2018

卷号：82

期号：7

起止页码：1073

外文期刊名：BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:000436822900002)、、EI(收录号：20182805532097)、Scopus(收录号：2-s2.0-85049577691)、WOS

基金：This research is based upon work that is supported by Grants from Guangdong Marine and Fishery Bureau [Z2014009 and B201601-Z10], the Department of Education of Guangdong Province [grant number: 2014GKXM049] and China Agriculture Research System [CARS-049]

语种：英文

外文关键词：Pinctada fucata martensii; growth traits; epidermal growth factor receptor; correlation analysis

外文摘要：Marine pearl production is directly influenced by the growth speed of Pinctada fucata martensii. However, the slow growth rate of this organism remains the main challenge in aquaculture production. Epidermal growth factor receptor (EGFR), an important receptor of tyrosine kinases in animals, plays versatile functions in development, growth and tissue regeneration. In this study, we described the characteristic and function of an EGFR gene identified from P. f. martensii (PmEGFR). PmEGFR possesses a typical EGFR structure and is expressed in all studied tissues, with the highest expression level in adductor muscle. PmEGFR expression level is significantly higher in the fast-growing group than that in the slow-growing one. Correlation analysis represents that shell height and shell weight show positive correlation with PmEGFR expression (p<0.05), and total weight and tissue weight exhibit positive correlation with it (p<0.01). This study indicates that PmEGFR is a valuable functional gene associated with growth traits.