文献类型：期刊文献

中文题名：姜黄素超分子包合物的结构鉴定及其抗氧化活性

英文题名：Structural identification of curcumin/β-cyclodextrin polymer inclusion complex and its antioxidant activity

作者：陈建平[1,2];彭莞仪[1];秦小明[1];谌素华[1];钟赛意[1];刘颖[3]

机构：[1]广东海洋大学食品科技学院,广东湛江524088;[2]广东省天然产物绿色加工与产品安全重点实验室,广东广州510640;[3]广东海洋大学农学院,广东湛江524088

年份：2017

卷号：38

期号：21

起止页码：21

中文期刊名：食品工业科技

外文期刊名：Science and Technology of Food Industry

收录：CSTPCD、、北大核心2014、CSCD_E2017_2018、北大核心、CSCD

基金：国家自然科学基金青年科学基金项目(21602034);广东省自然科学基金博士启动项目(2016A30310332);广东省天然产物绿色加工与产品安全重点实验室开放基金(201617);广东海洋大学科研启动项目(R17034)

语种：中文

中文关键词：姜黄素;β-环糊精聚合物;包合物制备;抗氧化活性

外文关键词：curcumin ;β-cyclodextrin polymer; inclusion complex preparation ; anti-oxidant activity

中文摘要：采用β-环糊精聚合物制备姜黄素超分子包合物并对其抗氧化活性进行测定。应用高效液相色谱法(HPLC)检测包合物中姜黄素的含量,并运用差示扫描量热仪(DSC)、傅立叶红外光谱仪(FT-IR)和X-射线衍射仪(XRD)对包合物进行结构鉴定。运用分光光度法测定包合物对ABTS和DPPH自由基的清除能力。研究表明,所制备的包合物得率和包合率分别为63.5%和34.5%。经DSC、FT-IR和XRD鉴定包合物已形成。抗氧化活性实验表明,包合物对ABTS自由基和DPPH自由基具有较好的清除能力,呈浓度和时间依赖性。实验结果表明,采用本实验方法可以成功获得具有一定抗氧化活性的姜黄素超分子包合物,这为姜黄素的剂型改善及其应用提供了新的技术手段和理论参考数据。

外文摘要：In this study, curcumin/β- cyclodextrin polymer inclusion complex were prepared by β- cyclodextrin polymer materials and its antioxidant activity was also studied.The content of curcumin in inclusion complex was detected by HPLC method and the structure of inclusion complex was identified by differential scanning calorimetry（ DSC）, X-ray diffractometry （XRD） and Fourier transform infrared spectroscopy（FT-IR） .Moreover, the spectrophotometric method was used to investigate the ability of inclusion complex to scavenge 2,2 - azinobis- 3- ethylbenzothiazoline-6 - sulfonic acid （ ABTS ） and 1,1 - diphenyl -2-picrylhydrazyl（DPPH） radicals.The experimental results showed that the yield and the encapsulation efficiency of inclusion complex was 63.5% and 34.5%, respectively.The formation of inclusion complex was proved by DSC, FT-IR, and XRD. Antioxidant activity assay analysis showed that inclusion complex exhibited strong scavenging effects on ABTS and DPPH free radicals in a dose-and time-dependent manner. The results demonstrated that inclusion complex with certain antioxidant activity could be obtained using the method reported in this paper, which provided the new technology method and theory reference data for the formulation improvement and application of curcumin.