文献类型：期刊文献

英文题名：Visible-light-mediated synthesis of 2-sulfenylated pyrrolo[1,2-α]quinoxalines via isocyanide/disulfide radical cascades

作者：Chen, Chen[1];Kong, Songzhi[1];Luo, Xiai[2];Wu, Minxia[3];Deng, Yazi[2];Luo, Xiaoke[2];Zheng, Pinjin[1];Xie, Haisheng[1]

机构：[1]Guangdong Ocean Univ, Coll Chem & Environm, Zhanjiang 524088, Peoples R China;[2]Hunan Univ Med, Sch Pharmaceut Sci, Hunan Prov Key Lab Synthet Biol Tradit Chinese Med, Huaihua 418000, Peoples R China;[3]North Paint & Coatings Ind Res & Design Inst Co Lt, Lanzhou 730101, Peoples R China

年份：2025

卷号：23

期号：24

起止页码：5857

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:001498735300001)、、EI(收录号：20252218537013)、Scopus(收录号：2-s2.0-105006886858)、WOS

基金：The authors are grateful to the Program for Scientific Research Startup Funds of Guangdong Ocean University (No. 060302122303). We are also grateful to the Natural Science Foundation of Hunan Province, China (2023JJ40465), and the Hunan Provincial Student Innovation and Entrepreneurship Training Program Introduction (S202312214015) for financial support.

语种：英文

外文关键词：Addition reactions - Cycloaddition - Free radical reactions - Photocatalysis - Reaction intermediates

外文摘要：We have developed a visible-light-driven photocatalytic tandem reaction system to achieve the efficient synthesis of 2-sulfenylated pyrrolo[1,2-alpha]quinoxalines based on a radical addition-cyclization mechanism. Mechanistic studies show that the sulfur radical intermediates generated in the reaction system directly participate in the subsequent formation of C-S bonds. This strategy has opened up an efficient synthetic pathway for the precise synthesis of C2-sulfur-substituted heterocyclic compounds.