文献类型：期刊文献

英文题名：Screening, characterization and mechanism of a potential stabiliser for nisin nanoliposomes with high encapsulation efficiency

作者：Li, Qibin[1];Lv, Linao[1];Liang, Weiqi[1];Chen, Zhibao[2];Deng, Qi[1];Sun, Lijun[1];Wang, Yaling[1];Liu, Ying[1,2]

机构：[1]Guangdong Ocean Univ, Key Lab Adv Proc Aquat Prod, Guangdong Prov Engn Technol Res Ctr Marine Food, Coll Food Sci & Technol,Guangdong Prov Key Lab Aqu, Zhanjiang 524088, Peoples R China;[2]Guangdong Ocean Univ, Coll Coastal Agr Sci, Zhanjiang 524088, Peoples R China

年份：2024

卷号：457

外文期刊名：FOOD CHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:001261164600001)、、EI(收录号：20242616422476)、Scopus(收录号：2-s2.0-85196866004)、WOS

基金：This work was funded by the Key Areas Special Project for Rural Revitalization in Guangdong Province's Ordinary Universities (grant numbers: 2020ZDZX1043), Special Project for Rural Revitalization (Announcing and Leading Technology Assistance Projects) (grant numbers: 080503042201) and Guangdong Province Science and Technology Project (grant numbers: 2017A030303079) .

语种：英文

外文关键词：Curcumin; Encapsulation efficiency; Nanoliposomes; Nisin; Stabiliser

外文摘要：The encapsulation efficiency (EE%) reflects the amount of bioactive components that can be loaded into nanoliposomes. Obtaining a suitable nanoliposome stabiliser may be the key to improving their EE%. In this study, three polyphenols were screened as stabilisers of nanoliposomes with high nisin EE%, with curcumin nanoliposomes (Cu-NLs) exhibiting the best performance (EE% = 95.94%). Characterizations of particle size, PDI and zeta potential indicate that the Cu-NLs had good uniformity and stability. TEM found that nisin accumulated at the edges of the Cu-NLs ' phospholipid layer. DSC and FT-IR revealed that curcumin was involved in the formation of the phospholipid layer and altered its structure. FT-IR and molecular docking simulations indicate that the interactions between curcumin and nisin are mainly hydrogen bonding and hydrophobic. In whole milk, Cu-NLs effectively protected nisin activity. This study provides an effective strategy for improving the EE% of nanoliposomes loaded with nisin and other bacteriocins.